A0A5E9LWF5 · A0A5E9LWF5_STAEP
- ProteinFluoride-specific ion channel FluC
- GenefluC
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids117 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
Catalytic activity
- fluoride(in) = fluoride(out)This reaction proceeds in the forward direction.
Activity regulation
Na+ is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 71 | Na+ (UniProtKB | ChEBI); structural | |||
Binding site | 74 | Na+ (UniProtKB | ChEBI); structural | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | fluoride channel activity | |
Molecular Function | metal ion binding | |
Biological Process | cellular detoxification of fluoride |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameFluoride-specific ion channel FluC
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Staphylococcaceae > Staphylococcus
Accessions
- Primary accessionA0A5E9LWF5
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 6-21 | Helical | |||
Transmembrane | 33-56 | Helical | |||
Transmembrane | 62-84 | Helical | |||
Transmembrane | 96-115 | Helical | |||
Keywords
- Cellular component
Structure
Sequence
- Sequence statusComplete
- Length117
- Mass (Da)12,819
- Last updated2019-11-13 v1
- ChecksumBF1F71F8B08D7FB5
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JADPYN010000037 EMBL· GenBank· DDBJ | MBF9304716.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
PEJG01000007 EMBL· GenBank· DDBJ | PIH10075.1 EMBL· GenBank· DDBJ | Genomic DNA |