A0A5E5RBC0 · A0A5E5RBC0_PSEAI

  • Protein
    Orotidine 5'-phosphate decarboxylase
  • Gene
    pyrF
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).

Catalytic activity

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.

Features

Showing features for binding site, active site.

123120406080100120140160180200220
TypeIDPosition(s)Description
Binding site13substrate
Binding site35substrate
Binding site62-71substrate
Active site64Proton donor
Binding site122substrate
Binding site182substrate
Binding site190substrate
Binding site210substrate
Binding site211substrate

GO annotations

AspectTerm
Molecular Functionorotidine-5'-phosphate decarboxylase activity
Biological Process'de novo' pyrimidine nucleobase biosynthetic process
Biological Process'de novo' UMP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Orotidine 5'-phosphate decarboxylase
  • EC number
  • Alternative names
    • OMP decarboxylase
      (OMPDCase
      ; OMPdecase
      )

Gene names

    • Name
      pyrF
    • ORF names
      TUEID40_05830

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • ID40
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas

Accessions

  • Primary accession
    A0A5E5RBC0

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain7-226Orotidine 5'-phosphate decarboxylase

Sequence similarities

Belongs to the OMP decarboxylase family. Type 1 subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    231
  • Mass (Da)
    24,549
  • Last updated
    2019-11-13 v1
  • Checksum
    F7D20F9988B253E9
MSACQSPIIVALDFPTREAALALADQLDPKLCRVKVGKELFTSCAAGIVETLRGKGFEVFLDLKFHDIPNTTAMAVKAAAEMGVWMVNVHCSGGLRMMAACRETLEAFSGPRPLLIGVTVLTSMEREDLAGIGLDIEPQEQVLRLAALAQKAGMDGLVCSAQEAPALKAAHPGLQLVTPGIRPRQRQDDQRRILTPRQALDAGSDYLVIGRPISQAADPAKALAAIVAELG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LR700248
EMBL· GenBank· DDBJ
VVH84619.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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