A0A5E5QWJ8 · A0A5E5QWJ8_PSEAI

  • Protein
    Aconitate hydratase B
  • Gene
    acnB
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 1 [4Fe-4S] cluster per subunit.

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.
Organic acid metabolism; propanoate degradation.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site191substrate
Binding site244-246substrate
Binding site417-419substrate
Binding site501substrate
Binding site713[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site772[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site775[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site794substrate
Binding site799substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Function2-methylisocitrate dehydratase activity
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functionaconitate hydratase activity
Molecular Functionmetal ion binding
Molecular FunctionRNA binding
Biological Processtricarboxylic acid cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Aconitate hydratase B
  • EC number
  • Alternative names
    • 2-methylisocitrate dehydratase

Gene names

    • Name
      acnB
    • ORF names
      TUEID40_00766

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • ID40
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas

Accessions

  • Primary accession
    A0A5E5QWJ8

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain4-156Aconitase B HEAT-like
Domain168-382Aconitase B swivel
Domain475-698Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Domain700-821Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha

Sequence similarities

Belongs to the aconitase/IPM isomerase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    869
  • Mass (Da)
    93,658
  • Last updated
    2019-11-13 v1
  • Checksum
    D994FC23DC18BC5B
MLEAYRKHVEERAAQGVVPQPLNAEQTAGLVELLKNPPAGEEEFLLDLITNRVPPGVDEAAYVKAGFLSAIVKGEATSPLIDKQRAAELLGTMQGGYNIATLVELLDDTELANTAAEQLKHTLLMFDAFHDVAERAKKGNAAAKSVLQSWADGEWFKAKPEVPEKLTLTVFKVPGETNTDDLSPAPDAWSRPDIPLHALAMLKMARDGIEPVQPGSVGPLKQIEAVKAKGFPVAYVGDVVGTGSSRKSATNSVLWFFGDDIPFVPNKRAGGFCFGTKIAPIFYNTMEDAGALPIEFDCTNLAMGDVIDVYPYEGKVVRHDSGEVVTTFELKTPVLLDEVRAGGRIPLIVGRGLTEKARAELGLGASDLFRKPEAPADSGKGFTLAQKMVGRACGLPEGQGVRPGTYCEPKMTTVGSQDTTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPKPIDVKTHHTLPDFIMTRGGVSLRPGDGIIHSWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVLVRFKGKLQPGITLRDLVHAIPYYAIQQGLLTVEKKGKKNIFSGRILEIEGLNDLTVEQAFELSDASAERSAAGCTIKLPEQAIAEYLKSNITLLRWMIGEGYGDPRTLERRAQAMEAWLAKPELLEADKDAEYAAVIEIDLADVKEPVLCAPNDPDDARLLSSVQGRKIDEVFIGSCMTNIGHFRAAGKLLDKVKGGIPTRLWLAPPTKMDAHQLTEEGYYGIYGKAGARMEMPGCSLCMGNQARVQTGSTVVSTSTRNFPNRLGDATDVFLASAELAAVSSILGKLPTVEEYMAYAKDIDSMAADVYRYLSFDQIAEFREAAANAKIPVVQA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LR700248
EMBL· GenBank· DDBJ
VVH79613.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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