A0A5E5PYK2 · A0A5E5PYK2_9GAMM

Function

function

Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

Catalytic activity

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site78S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site100S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site119S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site127S-adenosyl-L-methionine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionRNA binding
Molecular FunctiontRNA (5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase activity
Molecular FunctiontRNA (cytidine(34)-2'-O)-methyltransferase activity
Biological Processwobble position cytosine ribose methylation
Biological Processwobble position uridine ribose methylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA (cytidine(34)-2'-O)-methyltransferase
  • EC number
  • Alternative names
    • tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmL

Gene names

    • Name
      trmL
    • ORF names
      BAZOLSSOX_2650

Organism names

Accessions

  • Primary accession
    A0A5E5PYK2

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-139tRNA/rRNA methyltransferase SpoU type

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    153
  • Mass (Da)
    17,462
  • Last updated
    2019-11-13 v1
  • Checksum
    91FF901635C0E34B
MLNLVLFEPEIPNNTGSLIRLSANMGASLHLIKPFGFEMTDKRLRRAGLDYKELAQVFEYENFDHYLDKAKPERLFAVSSKVQTNYAEVEYQESDSFLFGPETRGLPQEILDRFEGITLPMQVGSRSLNLSNCVSIVAYEAWRQIGFIGAKYV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CABVGM010000145
EMBL· GenBank· DDBJ
VVH56569.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp