A0A5E4A6K3 · A0A5E4A6K3_MARMO
- ProteinCalponin-homology (CH) domain-containing protein
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids7221 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cell junction | |
Cellular Component | cell projection | |
Cellular Component | cytoplasm | |
Cellular Component | keratin filament | |
Cellular Component | plasma membrane | |
Molecular Function | calcium ion binding | |
Molecular Function | keratin filament binding | |
Molecular Function | microtubule binding | |
Molecular Function | structural molecule activity | |
Biological Process | intermediate filament bundle assembly | |
Biological Process | wound healing |
Keywords
- Ligand
Names & Taxonomy
Protein names
- Recommended nameCalponin-homology (CH) domain-containing protein
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Sciuromorpha > Sciuridae > Xerinae > Marmotini > Marmota
Accessions
- Primary accessionA0A5E4A6K3
Proteomes
Subcellular Location
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain, coiled coil, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-56 | Calponin-homology (CH) | ||||
Sequence: MERVQIQSNRENLEQAFEVAERLGVTRLLDAEDVDVPSPDEKSVITYVSSIYDAFP | ||||||
Coiled coil | 235-287 | |||||
Sequence: IQECEGLIRQLQVDLQILRDENYYQLEELAFRVMRLQDELVTLRLECTNLYRK | ||||||
Domain | 625-682 | SH3 | ||||
Sequence: KSTISVKAICDYRQIEITICKNDECVLEDNSQRTKWKVISPTGNEAMVPSVCFLIPPP | ||||||
Coiled coil | 1160-1190 | |||||
Sequence: VKYISDALRRLEEEEKVVEEEKQEHVEKVKD | ||||||
Coiled coil | 1254-1299 | |||||
Sequence: HKLSEKEKEQISERLDALNKAYHDLCDGSSSQLQQLQSQLAQQTEQ | ||||||
Region | 1942-1962 | Disordered | ||||
Sequence: KTKYTPSETGRPLLKSQSKNS | ||||||
Compositional bias | 2585-2620 | Basic and acidic residues | ||||
Sequence: RGKDKVRDSDGKQIKESKEISLEQLEDKDHDKWGAS | ||||||
Region | 2585-2647 | Disordered | ||||
Sequence: RGKDKVRDSDGKQIKESKEISLEQLEDKDHDKWGASADAKGSASVLSPSNLKGKSLDQVSVPH | ||||||
Compositional bias | 2626-2640 | Polar residues | ||||
Sequence: SASVLSPSNLKGKSL | ||||||
Compositional bias | 2757-2779 | Basic and acidic residues | ||||
Sequence: KLDQEMTRSEREKESDRDTGFSV | ||||||
Region | 2757-2793 | Disordered | ||||
Sequence: KLDQEMTRSEREKESDRDTGFSVTYKTEDSSSQVTPK | ||||||
Coiled coil | 3435-3469 | |||||
Sequence: LTALREKLHQAREQYEALQERTRVAQKELEQAVTS | ||||||
Coiled coil | 3599-3626 | |||||
Sequence: KEQYVASLAQSEAELKQVQTLRDELQKF | ||||||
Coiled coil | 3853-3907 | |||||
Sequence: SQSVQESLESLLQSIREVEQNLEGEQVASLSSGVIQEALANNMKLKQDIARQKSS | ||||||
Coiled coil | 3993-4060 | |||||
Sequence: IAHFSQQIQELTLEMTDQQENLDTLEHLVTALGSCGFALDLSQHQGRVQNLKRDFAELQKTVQEREKD | ||||||
Coiled coil | 4401-4476 | |||||
Sequence: IDQAIIKSTQYQELLQDLSEKVKAVGQRLSGQSAISTQPEAVKQQLEETSEIRSDLEQLDNEIKEAQTLCDELSVL | ||||||
Coiled coil | 4700-4755 | |||||
Sequence: EDGIRDEKAEINQNMDAITEELQAKTGLLEEMTQRLKEFQESFKNIERKVEGAKHQ | ||||||
Coiled coil | 4892-4938 | |||||
Sequence: IQSLKFDIEASEAECRQMLEEEGTLDLLGLKRELEALNKQCGKLTER | ||||||
Coiled coil | 5918-5945 | |||||
Sequence: NNAWENLNKTWKERLEKLEDAMQAAVQY | ||||||
Region | 6776-6808 | Disordered | ||||
Sequence: IEPSHGPFIEKSRSGSRKSLSQPTPPPMPILSQ | ||||||
Domain | 6868-6903 | EF-hand | ||||
Sequence: HKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFP | ||||||
Domain | 6904-6939 | EF-hand | ||||
Sequence: TTKLEMTAVADIFDRDGDGYIDYYEFVAALHPNKDA | ||||||
Domain | 6944-7022 | GAR | ||||
Sequence: TDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCR | ||||||
Region | 7038-7221 | Disordered | ||||
Sequence: PEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKVIPSAGSKLKRPTPTFHSSRTSLAGDTSNSSSPASTGAKTNRADPKKSASRPGSRAGSRAGSRASSRRGSDASDFDLLETQSACSDTSESSTAGGQGSSRRGLTKPSKIPTMSKKTSTASPRTPGPKR | ||||||
Compositional bias | 7057-7094 | Polar residues | ||||
Sequence: PSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKV | ||||||
Compositional bias | 7104-7136 | Polar residues | ||||
Sequence: RPTPTFHSSRTSLAGDTSNSSSPASTGAKTNRA | ||||||
Compositional bias | 7168-7221 | Polar residues | ||||
Sequence: FDLLETQSACSDTSESSTAGGQGSSRRGLTKPSKIPTMSKKTSTASPRTPGPKR |
Sequence similarities
Belongs to the plakin or cytolinker family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length7,221
- Mass (Da)819,595
- Last updated2019-11-13 v1
- Checksum8FFAE8FA721CC529
Computationally mapped potential isoform sequences
There are 5 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A5E4A4Y5 | A0A5E4A4Y5_MARMO | MONAX_5E008224 | 7281 | ||
A0A5E4A543 | A0A5E4A543_MARMO | MONAX_5E008224 | 7279 | ||
A0A5E4A5F9 | A0A5E4A5F9_MARMO | MONAX_5E008224 | 7157 | ||
A0A5E4A5Q9 | A0A5E4A5Q9_MARMO | MONAX_5E008224 | 5754 | ||
A0A5E4A6L7 | A0A5E4A6L7_MARMO | MONAX_5E008224 | 7244 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 2585-2620 | Basic and acidic residues | ||||
Sequence: RGKDKVRDSDGKQIKESKEISLEQLEDKDHDKWGAS | ||||||
Compositional bias | 2626-2640 | Polar residues | ||||
Sequence: SASVLSPSNLKGKSL | ||||||
Compositional bias | 2757-2779 | Basic and acidic residues | ||||
Sequence: KLDQEMTRSEREKESDRDTGFSV | ||||||
Compositional bias | 7057-7094 | Polar residues | ||||
Sequence: PSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKV | ||||||
Compositional bias | 7104-7136 | Polar residues | ||||
Sequence: RPTPTFHSSRTSLAGDTSNSSSPASTGAKTNRA | ||||||
Compositional bias | 7168-7221 | Polar residues | ||||
Sequence: FDLLETQSACSDTSESSTAGGQGSSRRGLTKPSKIPTMSKKTSTASPRTPGPKR |
Keywords
- Technical term