A0A5C8W7I3 · A0A5C8W7I3_9HYPH
- ProteinPhosphoglycolate phosphatase
- Genegph
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids227 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.
Catalytic activity
- 2-phosphoglycolate + H2O = glycolate + phosphate
Cofactor
Pathway
Organic acid metabolism; glycolate biosynthesis; glycolate from 2-phosphoglycolate: step 1/1.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 11 | Nucleophile | |||
Binding site | 11 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 13 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 173 | Mg2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | metal ion binding | |
Molecular Function | phosphoglycolate phosphatase activity | |
Biological Process | carbohydrate metabolic process | |
Biological Process | dephosphorylation | |
Biological Process | DNA repair | |
Biological Process | glycolate biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphoglycolate phosphatase
- EC number
- Short namesPGP ; PGPase
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Methylobacteriaceae > Methylobacterium
Accessions
- Primary accessionA0A5C8W7I3
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Sequence
- Sequence statusComplete
- Length227
- Mass (Da)24,111
- Last updated2019-11-13 v1
- MD5 ChecksumC1D395531CE33656AD9E14DBA924FC9A
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
VRVH01000332 EMBL· GenBank· DDBJ | TXN60998.1 EMBL· GenBank· DDBJ | Genomic DNA |