A0A5C8KNH4 · A0A5C8KNH4_9GAMM

Function

function

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.

Features

Showing features for site, active site, binding site.

TypeIDPosition(s)Description
Site92Transition state stabilizer
Active site96Proton acceptor
Binding site264Fe (UniProtKB | ChEBI) of heme b (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functioncatalase activity
Molecular Functionheme binding
Molecular Functionmetal ion binding
Biological Processcellular response to hydrogen peroxide
Biological Processhydrogen peroxide catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Catalase-peroxidase
  • EC number
  • Short names
    CP
  • Alternative names
    • Peroxidase/catalase

Gene names

    • Name
      katG
    • ORF names
      FU658_10340

Organism names

  • Taxonomic identifier
  • Strain
    • Alg18-2.2
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Lysobacterales > Lysobacteraceae > Alkalisalibacterium

Accessions

  • Primary accession
    A0A5C8KNH4

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for cross-link.

TypeIDPosition(s)Description
Cross-link223↔249Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-95)

Post-translational modification

Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.

Interaction

Subunit

Homodimer or homotetramer.

Family & Domains

Features

Showing features for compositional bias, region, domain.

TypeIDPosition(s)Description
Compositional bias1-23Basic and acidic residues
Region1-24Disordered
Domain129-425Plant heme peroxidase family profile
Region344-369Disordered
Compositional bias349-363Basic and acidic residues

Sequence similarities

Belongs to the peroxidase family. Peroxidase/catalase subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    741
  • Mass (Da)
    81,968
  • Last updated
    2019-11-13 v1
  • Checksum
    B8E199CF3835DCC6
MSDEAKCPFNGDAGKKPKGRRTNRDWWPNQLSLSMLHQGSRLSDPMDESFDYAKEFNSLDLDAVIKDLHEVMTDSQEWWPADYGHYGPLFIRMAWHSAGTYRVQDGRGGANTGGQRFAPLNSWPDNGNLDKARRLLWPIKKKYGRKLSWADLFILTGNVALESMGFKTFGFGGGREDIWEPREDIHWGPEEEWLATSDTENSRYSGDRELANPLAAVQMGLIYVNPQGPDGNPDPLASARDIRDTFARMAMDDEETVALVAGGHTFGKCHGAGEPDHVGAEPEGGDIVDQGFGWKNTFQSGVGTHAITSGLEGAWTNHPTKWDMGYFENLFGYEWELTKSPAGAHQWKPKGDAGKDSVPDAYDPNKRHQPMMSTADMAMRMDPAYEKISRRFKDNPQEFADAFARAWFKLTHRDMGPIARYLGPLVPKEELVWQDPVPAVDHPLVNDNDIAGLKKKLLDSGLSTEQLVSTAWASASTFRGSDMRGGANGARIRLAPQKDWEVNQPEELTKVLGVLEGIQKEFNGAQSGGKKVSLADLIVLGGCAAVEAAAKKGGVDIKVPFTPGRTDASQEQTDVESFNWLEPLADGFRNYVRKDMEVGDTEMLVDKAQLLTLTAPQMTVLLGGLRVLGANHGGSKHGVFTDRPGTLSNDFFRNLLDMGTVWERNSADKNLLEGKDRKTGKPKWTATVVDLVFGSNSQLRALAEVYASDDANEGYVHEFVRIWDKVMNLDRFDLGAGQTHG

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-23Basic and acidic residues
Compositional bias349-363Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VRTS01000007
EMBL· GenBank· DDBJ
TXK60972.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp