A0A5C7FDC2 · A0A5C7FDC2_9BACI

Function

function

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

Catalytic activity

Cofactor

Fe2+ (UniProtKB | Rhea| CHEBI:29033 )

Note: Binds 1 Fe2+ ion.

Features

Showing features for binding site, active site.

119320406080100120140160180
Type
IDPosition(s)Description
Binding site110Fe cation (UniProtKB | ChEBI)
Binding site153Fe cation (UniProtKB | ChEBI)
Active site154
Binding site157Fe cation (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionmetal ion binding
Molecular Functionpeptide deformylase activity
Biological Processpeptidyl-methionine modification
Biological Processtranslation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Peptide deformylase
  • EC number
  • Short names
    PDF
  • Alternative names
    • Polypeptide deformylase

Gene names

    • Name
      def
    • ORF names
      FTX54_010005
      , FTX54_01800

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • BZ-SZ-XJ29
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Alkalicoccus

Accessions

  • Primary accession
    A0A5C7FDC2

Proteomes

Family & Domains

Sequence similarities

Belongs to the polypeptide deformylase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    193
  • Mass (Da)
    22,066
  • Last updated
    2019-11-13 v1
  • Checksum
    6B32B37C6835E5AB
MLTMKDIIREGHPTLRKRAEEVSIPPSEKDIHTIQEMMEFLRNGQNEEIAAELELRPGVGLAAPQINISKRIICIRTPDAEDEVKEFALFNPKIISHSQETAFLESGEGCLSVDRAVEGIVPRYARIKVEAFTSDGEKVKLRFRGYEAIVIQHEIDHLDGIMFYDRIEDYNDKFKRPLPSKSVITRSENETVI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VPFE01000001
EMBL· GenBank· DDBJ
TXF87478.1
EMBL· GenBank· DDBJ
Genomic DNA
CP144914
EMBL· GenBank· DDBJ
WWD78761.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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