A0A5C7F139 · A0A5C7F139_9ACTN
- ProteinGlutamate--tRNA ligase
- GenegltX
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids491 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
Catalytic activity
- ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu)
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ATP binding | |
Molecular Function | glutamate-tRNA ligase activity | |
Molecular Function | tRNA binding | |
Molecular Function | zinc ion binding | |
Biological Process | glutamyl-tRNA aminoacylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlutamate--tRNA ligase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Coriobacteriia > Coriobacteriales > Coriobacteriaceae > Collinsella
Accessions
- Primary accessionA0A5C7F139
Proteomes
Subcellular Location
Interaction
Subunit
Monomer.
Structure
Family & Domains
Features
Showing features for domain, motif.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 4-323 | Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic | ||||
Sequence: NVRVRFAPSPTGKLHIGGARTAIYNWAFARANGGTFILRIDDTDPTRSTDENTQIILRAMRWLGLDWDEGPEVGGDFGPYSQTERLGLYKQTAERLLAEGKAYPCFCTPEQLAADREAAQARKDPFQGYQRRCRDLSPEEAQARIDAGEPYVLRIKVPQDRGNVVINDAVHGEVTFDAKELDDFVIFRSDGTPTYNFATVVDDALMGITHVIRGDDHLSNTPRQVIVYEAMGAPVPTFAHISMILGADGKKLSKRHGATSVEEYRDAGYLSDAFVNYLALLGWSLDGETTVIPRDVLASQFSLERISKNPATFDPKKLDW | ||||||
Motif | 11-21 | 'HIGH' region | ||||
Sequence: PSPTGKLHIGG | ||||||
Motif | 254-258 | 'KMSKS' region | ||||
Sequence: KLSKR | ||||||
Domain | 357-486 | Aminoacyl-tRNA synthetase class I anticodon-binding | ||||
Sequence: EADEAWVDALAAIVRPRTKMPADAAAVAAPVFMTAETLEYDEKSVSKGLAKEGMGAVLDAARAALEAVTEWTPAHIDAALEPLPEALDVKKRLVFGAVRVAECGNMVSPPLGETMALIGRDDCLARIDRA |
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length491
- Mass (Da)53,801
- Last updated2019-11-13 v1
- ChecksumA9E656F240A4C795
Keywords
- Technical term