A0A5C7ERN5 · A0A5C7ERN5_9ACTN
- ProteinRibonuclease 3
- Genernc
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids242 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
Catalytic activity
Cofactor
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | metal ion binding | |
Molecular Function | ribonuclease III activity | |
Molecular Function | rRNA binding | |
Biological Process | mRNA processing | |
Biological Process | rRNA processing | |
Biological Process | tRNA processing |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRibonuclease 3
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Coriobacteriia > Coriobacteriales > Coriobacteriaceae > Collinsella
Accessions
- Primary accessionA0A5C7ERN5
Proteomes
Subcellular Location
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 7-134 | RNase III | ||||
Sequence: ASRAEQICGYSFSDRSLLESALTHPSAVEGQPVSASYERLEFLGDSILGAVVAESLFRTYPGFDEGKLTRLKVSLVSGMTLSEVALELGIDECIVFGASETGTGARGLHSALENVYEALVGALYLDGG | ||||||
Domain | 160-229 | DRBM | ||||
Sequence: NPKSYLQERVQADHMEAPSYKLIGVDGPAHEPTFTAVAFVDGVRRGRGTGSSKKEAEAAAALDALNRMGY |
Sequence similarities
Belongs to the ribonuclease III family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length242
- Mass (Da)25,811
- Last updated2019-11-13 v1
- Checksum4D9E70143D490843
Keywords
- Technical term