A0A5C7ERN5 · A0A5C7ERN5_9ACTN

  • Protein
    Ribonuclease 3
  • Gene
    rnc
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • Endonucleolytic cleavage to 5'-phosphomonoester.
    EC:3.1.26.3 (UniProtKB | ENZYME | Rhea)

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, active site.

124220406080100120140160180200220240
TypeIDPosition(s)Description
Binding site47Mg2+ (UniProtKB | ChEBI)
Active site51
Binding site120Mg2+ (UniProtKB | ChEBI)
Active site123
Binding site123Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionmetal ion binding
Molecular Functionribonuclease III activity
Molecular FunctionrRNA binding
Biological ProcessmRNA processing
Biological ProcessrRNA processing
Biological ProcesstRNA processing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ribonuclease 3
  • EC number
  • Alternative names
    • Ribonuclease III
      (RNase III
      )

Gene names

    • Name
      rnc
    • ORF names
      E4J93_05035

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • BA40
  • Taxonomic lineage
    Bacteria > Actinomycetota > Coriobacteriia > Coriobacteriales > Coriobacteriaceae > Collinsella

Accessions

  • Primary accession
    A0A5C7ERN5

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain7-134RNase III
Domain160-229DRBM

Sequence similarities

Belongs to the ribonuclease III family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    242
  • Mass (Da)
    25,811
  • Last updated
    2019-11-13 v1
  • Checksum
    4D9E70143D490843
MSIAKKASRAEQICGYSFSDRSLLESALTHPSAVEGQPVSASYERLEFLGDSILGAVVAESLFRTYPGFDEGKLTRLKVSLVSGMTLSEVALELGIDECIVFGASETGTGARGLHSALENVYEALVGALYLDGGWQAAADFIARTLKPHLATERAEHPSNPKSYLQERVQADHMEAPSYKLIGVDGPAHEPTFTAVAFVDGVRRGRGTGSSKKEAEAAAALDALNRMGYTHNGVILKKKPGK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VOWY01000010
EMBL· GenBank· DDBJ
TXF36752.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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