A0A5C7EQN2 · A0A5C7EQN2_9ACTN

  • Protein
    Glycerol kinase
  • Gene
    glpK
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Activity regulation

Inhibited by fructose 1,6-bisphosphate (FBP).

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site30ADP (UniProtKB | ChEBI)
Binding site30ATP (UniProtKB | ChEBI)
Binding site30sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site31ATP (UniProtKB | ChEBI)
Binding site32ATP (UniProtKB | ChEBI)
Binding site34ADP (UniProtKB | ChEBI)
Binding site100glycerol (UniProtKB | ChEBI)
Binding site100sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site101glycerol (UniProtKB | ChEBI)
Binding site101sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site152glycerol (UniProtKB | ChEBI)
Binding site152sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site261glycerol (UniProtKB | ChEBI)
Binding site261sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site262glycerol (UniProtKB | ChEBI)
Binding site283ADP (UniProtKB | ChEBI)
Binding site283ATP (UniProtKB | ChEBI)
Binding site326ADP (UniProtKB | ChEBI)
Binding site326ATP (UniProtKB | ChEBI)
Binding site330ATP (UniProtKB | ChEBI)
Binding site427ADP (UniProtKB | ChEBI)
Binding site427ATP (UniProtKB | ChEBI)
Binding site431ADP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functionglycerol kinase activity
Biological Processglycerol catabolic process
Biological Processglycerol-3-phosphate metabolic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glycerol kinase
  • EC number
  • Alternative names
    • ATP:glycerol 3-phosphotransferase
    • Glycerokinase
      (GK
      )

Gene names

    • Name
      glpK
    • ORF names
      E4J93_02085

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • BA40
  • Taxonomic lineage
    Bacteria > Actinomycetota > Coriobacteriia > Coriobacteriales > Coriobacteriaceae > Collinsella

Accessions

  • Primary accession
    A0A5C7EQN2

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain22-268Carbohydrate kinase FGGY N-terminal
Domain279-466Carbohydrate kinase FGGY C-terminal

Sequence similarities

Belongs to the FGGY kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    514
  • Mass (Da)
    55,916
  • Last updated
    2019-11-13 v1
  • Checksum
    716642889FAF6AF6
MAFTLKDLGLVDTMYLPQGGKYIMALDSGTTSVRAIIVDEYDCIVAQASRAITTSYPELGWVEQDPMEILASQIAVMMEVQFKSGIHSDSIAAIGITNQRETTVVWDRDSGQPIYNAIGWQCRRTAPIADKLVHDGLTDVIRSKTGLKPDAYFSATKVKWILDNVAGAREAAEAGQLMFGTIDTWLIYNLTGGMVYATDYTNASRTMLFNIHTLEWDEELLKIFDIPHSMLPEVRWSSGEFGRVSSEIMTHTPPITGVAGDQQASFFGHCCFEPGDTKNTYGTGCFMLMNTGDEVVESKNGLVSTIGIAESGRISYALEGSIFHAGSVIQWLRDKLGIIADAGETAAIARSIPNNKGCYLVPAFSGLGAPWWDPDSRGLICGLTAASDRATLVRAACESMAYQTFDVLRAMEMDAGRKLESLSVDGAASRNEFIMQFQADLLGISVVQSESLETTALGAAYLAGLAVGYWEDREELVQNRAIGKCFQPAGNPVELARVLSGWHDAVARSRTVLQ

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VOWY01000003
EMBL· GenBank· DDBJ
TXF38278.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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