A0A5C6LSS4 · A0A5C6LSS4_9BACT

  • Protein
    Fructose-bisphosphate aldolase
  • Gene
    fbaA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 2 Zn2+ ions per subunit. One is catalytic and the other provides a structural contribution.

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site105Proton donor
Binding site106Zn2+ 1 (UniProtKB | ChEBI); catalytic
Binding site140Zn2+ 2 (UniProtKB | ChEBI)
Binding site170Zn2+ 2 (UniProtKB | ChEBI)
Binding site222Zn2+ 1 (UniProtKB | ChEBI); catalytic
Binding site223dihydroxyacetone phosphate (UniProtKB | ChEBI)
Binding site260Zn2+ 1 (UniProtKB | ChEBI); catalytic
Binding site261-263dihydroxyacetone phosphate (UniProtKB | ChEBI)
Binding site282-285dihydroxyacetone phosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionfructose-bisphosphate aldolase activity
Molecular Functionzinc ion binding
Biological Processgluconeogenesis
Biological Processglycolytic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Fructose-bisphosphate aldolase
  • EC number
  • Short names
    FBP aldolase

Gene names

    • Name
      fbaA
    • ORF names
      FEF09_11550

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • YS-16
  • Taxonomic lineage
    Bacteria > Bacteroidota > Chitinophagia > Chitinophagales > Chitinophagaceae > Chitinophaga

Accessions

  • Primary accession
    A0A5C6LSS4

Proteomes

Subcellular Location

Family & Domains

Sequence similarities

Belongs to the class II fructose-bisphosphate aldolase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    355
  • Mass (Da)
    39,231
  • Last updated
    2019-11-13 v1
  • Checksum
    878A050AAC4B4467
MGKYRAGVLFGEELEALYNDAKSNAFAMPAVNVVGTNSVNAVLETAAKVNSPVIIQFSNGGAQFFAGKGMPNDKLQANIAGAISGAKHVHEVAKYYGVPVVLHTDHAAKKWLPWIDGLLDAGEVFMKQTGQPLFSSHMLDLSEEPIHENIETSVKYFERMNKLGMSIEIELGVTGGEEDGVDNSGVENDKLYTQPEEVFYAYENLSKVGSRFTVAAAFGNVHGVYSPGNVELRPVILHNSQEFVQQKLGTAPKPIYYVFHGGSGSPKHQIAESLGYGVIKMNLDTDMQWAFWEGIHDFYEAKKDYLQAQLGNPEGADKPNKKYYDPRVWLRKGEETFVKRLEEAFADLNCVNRNA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VOHS01000009
EMBL· GenBank· DDBJ
TWW00311.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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