Essential maintenance is planned to begin on Tue Jan 28 2025. The website may be temporarily unavailable. Please use our fallback: https://wwwdev.ebi.ac.uk/uniprot/front-end/fallback/ during this time.

A0A5C6G7G3 · A0A5C6G7G3_9HYPO

  • Protein
    Chitin synthase
  • Gene
    CHS2_1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcell septum
Cellular Componentplasma membrane
Molecular Functionchitin synthase activity
Biological Processcell wall organization
Biological Processchitin biosynthetic process
Biological Processconidium formation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Chitin synthase
  • EC number

Gene names

    • Name
      CHS2_1
    • ORF names
      ED733_003194

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Cep018-CH2
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Hypocreales > Clavicipitaceae > Metarhizium

Accessions

  • Primary accession
    A0A5C6G7G3

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane580-603Helical
Transmembrane637-658Helical
Transmembrane670-695Helical
Transmembrane715-743Helical
Transmembrane755-772Helical
Transmembrane849-868Helical
Transmembrane889-912Helical

Keywords

PTM/Processing

Keywords

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region1-148Disordered
Compositional bias34-57Basic and acidic residues
Compositional bias76-117Polar residues
Domain152-230Chitin synthase N-terminal

Sequence similarities

Belongs to the chitin synthase family. Class III subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    924
  • Mass (Da)
    103,977
  • Last updated
    2019-11-13 v1
  • MD5 Checksum
    8596EF11405279C7C9CC3EC84C43EE2D
MAYNGHGHGQGHGQGREYGGHPMQDLPSGNDYHIPPQDHDEDARGYLLNEPSPHHYEHGRLGVGTPPDRPVSAYSLTESYAPNASQLPPAGSGSFSDSGFGQYGQQHQQQQGFGNPYDRPLSSVHDEEESWMQRQQQPGGMGQGGGLKRYNTRKVKLVQGSVLSIDYPVPSAIKNAVQPRYRDVEGGNEEFMKMRYTAATCDPNDFTLKNGYDLRPRMYNRHTELLIAITYYNEDKVLLSRTLHGVMQNIRDIVNLKKSTFWNKGGPAWQKIVVCLVFDGIEKADKNTLDILATVGVYQDGVIKKDVDGKETVAHIFEYTSQLSVTPSQQLIRPTGDSPQNLPPVQFIFCLKQKNSKKINSHRWLFNAFGRILNPEVSILIDAGTKPSPRSLLALWEGFYNDKDLGGACGEIHAMLGKGGKKLVNPLVAVQNFEYKISNILDKPLESSFGYVSVLPGAFSAYRFRAIMGRPLEQYFHGDHTLSKLLGKKGIDGMNIFKKNMFLAEDRILCFELVAKAGQKWHLTYIKAARGETDVPEGAAEFISQRRRWLNGSFAASLYSLMHFGRLYKSGHNIIRMFFFHIQMIYNVLNVIFSWFSLASYYLTTTVIMDIVGTPVVASNAASEHHGWPFGDAATPIVNALLKYLYLAFVILQFILALGNRPKGSKFTYIASFMVFGLIQGYILVLSGYLVARAFQQPITEQIRLDSSEDFVRSFFSGSSAAGVILIALVTIYGLYFLASFLYLDPWHMFHSFPYYMLLMSTYINILMVYAFNNWHDVSWGTKGSDKAEALPSANVTKGEKNEVVVEEIEKEQEDIDSQFEQTVRRALAPFKEVEEIEKKDVEDSYKSFRTGLVVSWLFSNILLVVVITSDNFNSFRIGESASVRTANFFKFLLYATAALSIVRFIGFLWFLGKTGIMCCFARR

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias34-57Basic and acidic residues
Compositional bias76-117Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
SBHS01000027
EMBL· GenBank· DDBJ
TWU72518.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help