A0A5C6AFS1 · A0A5C6AFS1_9BACT
- ProteinProtein-L-isoaspartate O-methyltransferase
- Genepcm
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids407 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
Catalytic activity
- [protein]-L-isoaspartate + S-adenosyl-L-methionine = [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 87 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity | |
Biological Process | methylation | |
Biological Process | protein modification process | |
Biological Process | protein repair |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProtein-L-isoaspartate O-methyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Planctomycetota > Planctomycetia > Pirellulales > Lacipirellulaceae > Botrimarina
Accessions
- Primary accessionA0A5C6AFS1
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-22 | ||||
Chain | PRO_5023145187 | 23-407 | Protein-L-isoaspartate O-methyltransferase | ||
Structure
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length407
- Mass (Da)44,826
- Last updated2019-11-13 v1
- MD5 Checksum3CC63234A026DC90346C826F46CF6B73
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
SJPR01000002 EMBL· GenBank· DDBJ | TWT97911.1 EMBL· GenBank· DDBJ | Genomic DNA |