A0A5B9EQG1 · A0A5B9EQG1_9RHOB
- ProteinPeptide methionine sulfoxide reductase MsrA
- GenemsrA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids220 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
Catalytic activity
- [thioredoxin]-disulfide + L-methionine + H2O = L-methionine (S)-S-oxide + [thioredoxin]-dithiol
RHEA-COMP:10700 CHEBI:50058 Position: n/n+3+ CHEBI:57844 + CHEBI:15377 = CHEBI:58772 + RHEA-COMP:10698 CHEBI:29950 Position: nCHEBI:29950 Position: n+3
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 42 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | L-methionine:thioredoxin-disulfide S-oxidoreductase activity | |
Molecular Function | peptide-methionine (S)-S-oxide reductase activity | |
Biological Process | protein modification process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePeptide methionine sulfoxide reductase MsrA
- EC number
- Short namesProtein-methionine-S-oxide reductase
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Rhodobacterales > Roseobacteraceae > Octadecabacter
Accessions
- Primary accessionA0A5B9EQG1
Proteomes
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-30 | ||||
Chain | PRO_5022771380 | 31-220 | Peptide methionine sulfoxide reductase MsrA | ||
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 36-177 | Peptide methionine sulphoxide reductase MsrA | |||
Sequence similarities
Belongs to the MsrA Met sulfoxide reductase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length220
- Mass (Da)24,185
- Last updated2019-11-13 v1
- MD5 Checksum07964863744704B7A651A7C1D32C784C
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP042819 EMBL· GenBank· DDBJ | QEE37083.1 EMBL· GenBank· DDBJ | Genomic DNA |