A0A5B9DBM9 · A0A5B9DBM9_9ARCH

Function

Catalytic activity

  • ATP-dependent breakage, passage and rejoining of double-stranded DNA.
    EC:5.6.2.2 (UniProtKB | ENZYME | Rhea)

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular FunctionATP binding
Molecular FunctionDNA binding
Molecular FunctionDNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
Molecular Functionmetal ion binding
Biological ProcessDNA topological change

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA topoisomerase (ATP-hydrolyzing)
  • EC number

Gene names

    • Name
      gyrB
    • ORF names
      DSAG12_02205

Organism names

  • Taxonomic identifier
  • Strain
    • MK-D1
  • Taxonomic lineage
    Archaea > Asgard group > Candidatus Lokiarchaeota > Candidatus Lokiarchaeia > Candidatus Prometheoarchaeales > Candidatus Prometheoarchaeaceae > Candidatus Prometheoarchaeum

Accessions

  • Primary accession
    A0A5B9DBM9

Proteomes

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region1-56Disordered
Compositional bias10-30Basic and acidic residues
Compositional bias35-56Polar residues
Domain499-629Toprim

Sequence similarities

Belongs to the type II topoisomerase GyrB family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    740
  • Mass (Da)
    84,143
  • Last updated
    2019-11-13 v1
  • Checksum
    339AC38C2AB20F46
MSSKKIQLKIKGDLNNKNKTETKDKNDSAENIVVQEGLEESNKNTPSQNEEITPKAINKNEFQQKTSKPESKIKKDYNAENIVVLEGLEGIRKRPSMYIGSQGRRGFHHLAFEVIDNSIDEVIGGFCSKIQVILEADNSCTIRDNGRGIPVSKHPKKGVSSLEIVFTSLHSGGKFDKKSYAVSGGLHGVGLAVVNACSEWSTAKVRRNGKLYKIKMARGHIIDHLSERETDRALDDTGTEIQFLPDKEIFTGMEEEQYLFDYDYLAGRLRDLAYLNPIEIEIIDRRAEKEKSEIFKYEDGLADFVNYLNKAKKTLHENIVHFKKKSNGIIVELSFQYNESYNEIVQSFVNNINTIEGGTHLTGFKSALSRVFNNYIKDHQSQFKNLKDKTLKGTDVREGIVAILSVSVPEPQFEGQTKTKLGNPEVKTIVSDIVYEEVYHHFDSNPKETKSIIHKCISAQQARLASQKARELTRRKSALETLRLPGKLADCSSKKAEECEIFIVEGDSAGGSAKQGRNRSTQAILPLRGKILNVEKSRIGKILENKEIAAMIKAIGVGIDEGKNNGDEEDDDDDEESQFDISQLRYHKIIIMCDADVDGHHIETLLLTFFFRYMRPLIDEGHIYLAVPPIYKLNYKNKFKYLYIADEAKLLNAELESFMKEHKISDISKIKVQRYKGLGEMNPEELWDTTMEPENRRLIRVKYDDFTNTDILFSILMGSEVAPRREYIVENYNKVLNLDI

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias10-30Basic and acidic residues
Compositional bias35-56Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP042905
EMBL· GenBank· DDBJ
QEE16375.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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