A0A5B9AQS0 · A0A5B9AQS0_ECOLX

  • Protein
    Diacylglycerol kinase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Mn2+, Zn2+, Cd2+ and Co2+ support activity to lesser extents.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site10ATP (UniProtKB | ChEBI)
Binding site10substrate
Binding site17ATP (UniProtKB | ChEBI)
Binding site23-26substrate
Binding site29ATP (UniProtKB | ChEBI)
Binding site29a divalent metal cation (UniProtKB | ChEBI)
Binding site31-35substrate
Binding site48-51substrate
Binding site56substrate
Active site70Proton acceptor
Binding site70substrate
Binding site77ATP (UniProtKB | ChEBI)
Binding site77a divalent metal cation (UniProtKB | ChEBI)
Binding site86-88ATP (UniProtKB | ChEBI)
Binding site95-96ATP (UniProtKB | ChEBI)
Binding site99substrate
Binding site113-118substrate

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular FunctionATP binding
Molecular FunctionATP-dependent diacylglycerol kinase activity
Molecular Functionmetal ion binding
Biological Processphosphatidic acid biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Diacylglycerol kinase
  • EC number

Gene names

    • ORF names
      FTV93_16630

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • NCYU-26-73
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Escherichia

Accessions

  • Primary accession
    A0A5B9AQS0

Proteomes

Subcellular Location

Cell inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane30-51Helical
Transmembrane97-118Helical

Keywords

Family & Domains

Sequence similarities

Belongs to the bacterial diacylglycerol kinase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    121
  • Mass (Da)
    13,124
  • Last updated
    2019-11-13 v1
  • MD5 Checksum
    D439F519DF09E48DA94A3CC516BCA2FC
MANNTTGLTRIIKAAGYSRKGLRAAWINEAAFRQEGVAVLLAVVIACWLDVDAITRVLLISSVMLVMIVEILNSAIEAVVDRIGSEYHELSGRAKDMGSAAVLIAIIVAVITWCILLWSHF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP042615
EMBL· GenBank· DDBJ
QED74908.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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