A0A5B6W7V7 · A0A5B6W7V7_9ROSI
- ProteinHypoxanthine phosphoribosyltransferase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids189 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate
Cofactor
Pathway
Purine metabolism; IMP biosynthesis via salvage pathway; IMP from hypoxanthine: step 1/1.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | guanine phosphoribosyltransferase activity | |
Molecular Function | hypoxanthine phosphoribosyltransferase activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | nucleotide binding | |
Biological Process | GMP salvage | |
Biological Process | guanine salvage | |
Biological Process | hypoxanthine metabolic process | |
Biological Process | IMP salvage | |
Biological Process | purine ribonucleoside salvage |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameHypoxanthine phosphoribosyltransferase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Malvales > Malvaceae > Malvoideae > Gossypium
Accessions
- Primary accessionA0A5B6W7V7
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 16-170 | Phosphoribosyltransferase | ||||
Sequence: QDQILDRVAQIASQITLDFKAAPDPPLFVGVATGAFLFLADLVKKVQLPLSVDLVRAQSYGSGTLSNGAPSISLDLKLDVKGKHVILVEDIVDTGYTLSCLIEHLEAKGVSSVSICAFLDKPTRRKVHIKLVGDGKFYKGFECPDYFVVGYGMDF |
Sequence similarities
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length189
- Mass (Da)20,850
- Last updated2019-11-13 v1
- Checksum94ABB75505CB9DA4
Keywords
- Technical term