A0A5B6UQC0 · A0A5B6UQC0_9ROSI
- ProteinAsparagine synthetase [glutamine-hydrolyzing]
- Geneasns
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids590 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
Catalytic activity
- ATP + H2O + L-aspartate + L-glutamine = AMP + diphosphate + H+ + L-asparagine + L-glutamate
Pathway
Amino-acid biosynthesis; L-asparagine biosynthesis; L-asparagine from L-aspartate (L-Gln route): step 1/1.
Features
Showing features for active site, binding site, site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 2 | For GATase activity | ||||
Sequence: C | ||||||
Binding site | 104 | L-glutamine (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 237 | ATP (UniProtKB | ChEBI) | ||||
Sequence: L | ||||||
Binding site | 273 | ATP (UniProtKB | ChEBI) | ||||
Sequence: V | ||||||
Binding site | 347-348 | ATP (UniProtKB | ChEBI) | ||||
Sequence: SG | ||||||
Site | 349 | Important for beta-aspartyl-AMP intermediate formation | ||||
Sequence: E |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | asparagine synthase (glutamine-hydrolyzing) activity | |
Molecular Function | ATP binding | |
Biological Process | asparagine biosynthetic process | |
Biological Process | glutamine metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAsparagine synthetase [glutamine-hydrolyzing]
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Malvales > Malvaceae > Malvoideae > Gossypium
Accessions
- Primary accessionA0A5B6UQC0
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 2-191 | Glutamine amidotransferase type-2 | ||||
Sequence: CGILAVLGCSDDSQAKRVRVLELSRRQIHIFFLLATFDDWSGLHQHGDCYLAHQRLAIVDPASGDQPLFNEDKSVVVTVNGEIYNHEELRKKLVNHKFRTGSDCDVIAHLYEEYGEDFVDMLDGIFSFVLLDTRDNSYIVARDAIGVTSLYIGWGLDGSIWISSEMKGLNDDCEHFECFPPGHLYSSKTG |
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length590
- Mass (Da)66,621
- Last updated2019-11-13 v1
- ChecksumACCF19399A6FDF62
Keywords
- Technical term