A0A5B3GSG5 · A0A5B3GSG5_9BACT
- ProteinPyrroline-5-carboxylate reductase
- GeneproC
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids260 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
Catalytic activity
- L-proline + NAD+ = 1-pyrroline-5-carboxylate + 2 H+ + NADH
Pathway
Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | pyrroline-5-carboxylate reductase activity | |
Biological Process | L-proline biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePyrroline-5-carboxylate reductase
- EC number
- Short namesP5C reductase ; P5CR
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacteroidota > Bacteroidia > Bacteroidales > Rikenellaceae > Alistipes
Accessions
- Primary accessionA0A5B3GSG5
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-16 | |||||
Sequence: MKVGFIGFGNMAQALA | ||||||
Chain | PRO_5024357232 | 17-260 | Pyrroline-5-carboxylate reductase | |||
Sequence: AGLAASGALQPGQIGACARDRAKLHRNTKPHGFLAFDDAAGVAGFADVVVVAVKPYQVEAVLAPVKGMLAGKVVVSVAAGMTFDRYEEILAPGTHHLSTIPNTPVAVCEGIVVCERRHSLSEAEWQSVQALLSHVGLVVTVDTAQLGIAGTVCGCGPAFVAMFIEALADAAVKHGIVRADAYRMASQMVVGTGKLQLATGQHPAVMKDAVCSPGGTTIVGVAELERKRFRGAVIDAIDAIQDKK |
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 2-96 | Pyrroline-5-carboxylate reductase catalytic N-terminal | ||||
Sequence: KVGFIGFGNMAQALAAGLAASGALQPGQIGACARDRAKLHRNTKPHGFLAFDDAAGVAGFADVVVVAVKPYQVEAVLAPVKGMLAGKVVVSVAAG | ||||||
Domain | 161-259 | Pyrroline-5-carboxylate reductase dimerisation | ||||
Sequence: QLGIAGTVCGCGPAFVAMFIEALADAAVKHGIVRADAYRMASQMVVGTGKLQLATGQHPAVMKDAVCSPGGTTIVGVAELERKRFRGAVIDAIDAIQDK |
Sequence similarities
Belongs to the pyrroline-5-carboxylate reductase family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length260
- Mass (Da)26,851
- Last updated2020-02-26 v1
- Checksum96726C233FF849A7