A0A5A7PQG9 · A0A5A7PQG9_STRAF
- ProteinE1 ubiquitin-activating enzyme
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1148 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP.
Catalytic activity
Pathway
Protein modification; protein ubiquitination.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 724 | Glycyl thioester intermediate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | nucleus | |
Molecular Function | ATP binding | |
Molecular Function | ubiquitin activating enzyme activity | |
Biological Process | DNA damage response | |
Biological Process | ubiquitin-dependent protein catabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameE1 ubiquitin-activating enzyme
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > asterids > lamiids > Lamiales > Orobanchaceae > Buchnereae > Striga
Accessions
- Primary accessionA0A5A7PQG9
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 30-49 | Polar residues | |||
Region | 30-51 | Disordered | |||
Domain | 1021-1143 | Ubiquitin-activating enzyme E1 C-terminal | |||
Sequence similarities
Belongs to the ubiquitin-activating E1 family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,148
- Mass (Da)128,641
- Last updated2019-11-13 v1
- Checksum8BEFD92A453EC675
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 30-49 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BKCP01004949 EMBL· GenBank· DDBJ | GER34712.1 EMBL· GenBank· DDBJ | Genomic DNA |