A0A571BFW3 · A0A571BFW3_MOUSE
- ProteinSodium channel, voltage-gated, type III, alpha
- GeneScn3a
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids880 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score1/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | monoatomic cation channel activity |
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionA0A571BFW3
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 124-147 | Helical | ||||
Sequence: ILVHSLFSMLIMCTILTNCVFMTL | ||||||
Transmembrane | 192-211 | Helical | ||||
Sequence: WLDFSVIVMAYVTEFVDLGN | ||||||
Transmembrane | 223-244 | Helical | ||||
Sequence: ALKTISVIPGLKTIVGALIQSV | ||||||
Transmembrane | 250-270 | Helical | ||||
Sequence: VMILTVFCLSVFALIGLQLFM | ||||||
Transmembrane | 400-427 | Helical | ||||
Sequence: YMIFFVLVIFLGSFYLVNLILAVVAMAY | ||||||
Transmembrane | 752-776 | Helical | ||||
Sequence: LVNLIVMDPFVDLAITICIVLNTLF | ||||||
Transmembrane | 788-809 | Helical | ||||
Sequence: FSSVLTVGNLVFTGIFTAEMVL | ||||||
Transmembrane | 829-850 | Helical | ||||
Sequence: GIIVSLSLMELGLANVEGLSVL |
Keywords
- Cellular component
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain, coiled coil.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 28-53 | Basic and acidic residues | ||||
Sequence: RAAEEKAKKPKKEQDIDDENKPKPNS | ||||||
Region | 28-60 | Disordered | ||||
Sequence: RAAEEKAKKPKKEQDIDDENKPKPNSDLEAGKN | ||||||
Domain | 127-433 | Ion transport | ||||
Sequence: HSLFSMLIMCTILTNCVFMTLSNPPDWTKNVEYTFTGIYTFESLIKILARGFCLEDFTFLRDPWNWLDFSVIVMAYVTEFVDLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCLQWPPSDSAFEINTTSYFNGTMDSNGTFVNVTMSTFNWKDYIADDSHFYVLDGQKDPLLCGNGSDAGQCPEGYICVKAGRNPNYGYTSFDTFSWAFLSLFRLMTQDYWENLYQLTLRAAGKTYMIFFVLVIFLGSFYLVNLILAVVAMAYEEQNQA | ||||||
Coiled coil | 424-465 | |||||
Sequence: AMAYEEQNQATLEEAEQKEAEFQQMLEQLKKQQEEAQAVAAA | ||||||
Region | 493-529 | Disordered | ||||
Sequence: SKSAKEWRNRRKKRRQREHLEGNHRPEGDRFPKSESE | ||||||
Compositional bias | 497-511 | Basic residues | ||||
Sequence: KEWRNRRKKRRQREH | ||||||
Compositional bias | 512-529 | Basic and acidic residues | ||||
Sequence: LEGNHRPEGDRFPKSESE | ||||||
Domain | 558-710 | Voltage-gated Na+ ion channel cytoplasmic | ||||
Sequence: SLLSIRGSLFSPRRNSKTSIFSFRGRAKDVGSENDFADDEHSTFEDSESRRDSLFVPHRPGERRNSNVSQASMSSRMVPGLPANGKMHSTVDCNGVVSLVGGPSALTSPTGQLPPEGTTTETEVRKRRLSSYQISMEMLEDSSGRQRAMSIAS | ||||||
Compositional bias | 587-616 | Basic and acidic residues | ||||
Sequence: VGSENDFADDEHSTFEDSESRRDSLFVPHR | ||||||
Region | 587-631 | Disordered | ||||
Sequence: VGSENDFADDEHSTFEDSESRRDSLFVPHRPGERRNSNVSQASMS | ||||||
Domain | 760-879 | Ion transport | ||||
Sequence: PFVDLAITICIVLNTLFMAMEHYPMTEQFSSVLTVGNLVFTGIFTAEMVLKIIAMDPYYYFQEGWNIFDGIIVSLSLMELGLANVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSV |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusFragment
- Length880
- Mass (Da)99,094
- Last updated2019-10-16 v1
- Checksum306984708E0BF5AA
Computationally mapped potential isoform sequences
There are 5 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A2ASI5 | SCN3A_MOUSE | Scn3a | 1947 | ||
A9JQD4 | A9JQD4_MOUSE | Scn3a | 137 | ||
A0A571BEB6 | A0A571BEB6_MOUSE | Scn3a | 328 | ||
A0A571BG54 | A0A571BG54_MOUSE | Scn3a | 428 | ||
F6U9Y2 | F6U9Y2_MOUSE | Scn3a | 122 |
Features
Showing features for compositional bias, non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 28-53 | Basic and acidic residues | ||||
Sequence: RAAEEKAKKPKKEQDIDDENKPKPNS | ||||||
Compositional bias | 497-511 | Basic residues | ||||
Sequence: KEWRNRRKKRRQREH | ||||||
Compositional bias | 512-529 | Basic and acidic residues | ||||
Sequence: LEGNHRPEGDRFPKSESE | ||||||
Compositional bias | 587-616 | Basic and acidic residues | ||||
Sequence: VGSENDFADDEHSTFEDSESRRDSLFVPHR | ||||||
Non-terminal residue | 880 | |||||
Sequence: G |
Keywords
- Technical term