A0A562CYV5 · A0A562CYV5_9GAMM

Function

function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentDNA-directed RNA polymerase complex
Molecular FunctionDNA binding
Molecular FunctionDNA-directed 5'-3' RNA polymerase activity
Molecular Functionribonucleoside binding
Biological ProcessDNA-templated transcription

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA-directed RNA polymerase subunit beta
  • EC number
  • Short names
    RNAP subunit beta
  • Alternative names
    • RNA polymerase subunit beta
    • Transcriptase subunit beta

Gene names

    • Name
      rpoB
    • ORF names
      L613_009000000080

Organism names

Accessions

  • Primary accession
    A0A562CYV5

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

Family & Domains

Features

Showing features for domain, coiled coil.

TypeIDPosition(s)Description
Domain28-526RNA polymerase beta subunit protrusion
Domain156-229RNA polymerase Rpb2
Domain361-417RNA polymerase Rpb2
Domain449-481RNA polymerase Rpb2
Domain540-607RNA polymerase Rpb2
Domain618-683DNA-directed RNA polymerase beta subunit external 1
Domain745-1317DNA-directed RNA polymerase subunit 2 hybrid-binding
Coiled coil1044-1071
Domain1319-1394RNA polymerase Rpb2

Sequence similarities

Belongs to the RNA polymerase beta chain family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,395
  • Mass (Da)
    156,001
  • Last updated
    2019-10-16 v1
  • Checksum
    6F2B2239FBB0B409
MTTYSFTEKKRIRKDFGKQRSILEVPFLLAIQVDSYREFLQADTDPAKRRDTGLHAALKSVFPIVSYSGNAALEYVGYKLGEPVFDERECRNRGLSYGAPLRVTVRLVIYDRESSTKAIKYVKEQEVYLGEIPLMTEHGTFIVNGTERVIVSQLHRSPGVFFDHDRGKTHSSGKLLYSARIIPYRGSWLDFEFDPKDALYTRIDRRRKLPVTILLRALGYNNEEMLRAFFEINTFHILPEGVQLELVPERLRGETLGFDLSDGEKVIVEAGKRITARHVRQLEQSGITALAVPDEYLLGRILAHDVVDANTGELLAAANDEITDEHLAAFRKAGVSSIGTLWVNDLDRGPYLSNTLRIDPTRTQLEALVEIYRMMRPGEPPTKEAAQNLFHNLFFTFERYDLSAVGRMKFNRRVGRKDVVGPAVLYDHKYFAERADDESKALVSEQGETSDILDVLRVLTEIRNGRGVVDDIDHLGNRRVRSVGEMAENVFRVGLVRVERAVKERLSMAESEGLTPQELINAKPVAAAIKEFFGSSQLSQFMDQNNPLSEVTHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCTIETPEGPNIGLINSLAVFARTNQYGFLETPYRKVVDGRITDEVEYLSAIEENEYVIAQVNAAHDKEGRLTEAFVPCRHQGESLLKPASEIHYMDVSPMQTVSVAAALVPFLEHDDANRALMGANMQRQAVPTLRAQTPLVGTGIERAVARDSGVTVNARRGGEVVQVDAGRIVVKVNEEEISGEQDAGVDIYTLTKYTRSNQNTCINQRPLVHVGDVVARGDVLADGPSTDIGELALGQNMLIAFMPWNGYNFEDSILLSERVVQEDRYTTIHIEELTCVARDTKLGPEEITADIPNVSEQALGRLDESGVVYIGAEVRAGDILVGKVTPKGESQLTPEEKLLRAIFGEKASDVKDSSLRVPPGMDGTVIDVQVFTRDGIEKDKRAKQIEENEIRRVKKDFDDQFRILEAAIYARLRTQIVGKVANGGPGLKKGDTITDAYLDGLKKSDWFALRMKDDDAAEAIERAQKQIQAHEKEFERRFADKRGKITQGDDLAPGVLKMVKVFLAVKRRIQPGDKMAGRHGNKGVVSNVVPVEDMPYMADGTPVDICLNPLGVPSRMNIGQILEVHLGWAAKGLGKRIQKMLDEQRAVSELREFLGKVYNHDNELFGQRVDLSQFSDEELVAMARNLTDGVPMATPVFDGAHEEEIRQMLELAYPDDDPETARLGFNASKTQMQLYDGRTGEAFDRKTTVGYMHYLKLNHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVQGRNQMYKNIVDGNHEMVAGMPESFNVLVKEIRSLAINMELEDE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VLJS01000125
EMBL· GenBank· DDBJ
TWH02635.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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