A0A562CWR7 · A0A562CWR7_9GAMM

Function

function

Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.
    EC:3.2.1.52 (UniProtKB | ENZYME | Rhea)

Pathway

Cell wall biogenesis; peptidoglycan recycling.

Features

Showing features for binding site, site, active site.

133250100150200250300
TypeIDPosition(s)Description
Binding site60substrate
Binding site68substrate
Binding site133substrate
Binding site163-164substrate
Site174Important for catalytic activity
Active site176Proton donor/acceptor
Active site247Nucleophile

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionbeta-N-acetylhexosaminidase activity
Molecular FunctionN-acetyl-beta-D-galactosaminidase activity
Biological Processcarbohydrate metabolic process
Biological Processcell division
Biological Processcell wall organization
Biological Processpeptidoglycan biosynthetic process
Biological Processpeptidoglycan turnover
Biological Processregulation of cell shape

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Beta-hexosaminidase
  • EC number
  • Alternative names
    • Beta-N-acetylhexosaminidase
    • N-acetyl-beta-glucosaminidase

Gene names

    • Name
      nagZ
    • ORF names
      L613_009800000070

Organism names

Accessions

  • Primary accession
    A0A562CWR7

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain10-288Glycoside hydrolase family 3 N-terminal

Sequence similarities

Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    332
  • Mass (Da)
    35,189
  • Last updated
    2019-10-16 v1
  • Checksum
    2ACE9AB65C1509E8
MLLIGVAGTELTAQERDWLQHDAVAGVILFKRNFASRAQVAELAAAIREAAPRPQLVCVDQEGGRVQRFREGYSDLPPLQRIGELYARDREAALALAEEHAWLMASEIRASGVDLSFAPVADLGRGNLAIGDRAFGPDPQAVAELVRAYVRGMHSVGMAATLKHFPGHGTVLEDTHVDHAVDPRPLQALRGEDLVPFVAGIEAGADAVMMAHVQYPAIAPDPAGYSPFWIGQFLRGELGFRGVVFSDDIGMAAAHAAGGVRARVLAHLDAGCDVVLVCHPELVAESLQAVRDRPLNTAALLGLLGRGALGWDGLLADARHAGARARLPSSAA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VLJS01000133
EMBL· GenBank· DDBJ
TWH01920.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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