A0A550D551 · A0A550D551_9CREN
- ProteinOrotidine 5'-phosphate decarboxylase
- GenepyrF
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids209 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
Catalytic activity
- orotidine 5'-phosphate + H+ = UMP + CO2
Pathway
Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 6 | substrate | |||
Binding site | 25 | substrate | |||
Active site | 54 | For OMPdecase activity | |||
Binding site | 54-63 | substrate | |||
Active site | 56 | For OMPdecase activity | |||
Active site | 56 | Proton donor | |||
Active site | 59 | For OMPdecase activity | |||
Binding site | 110 | substrate | |||
Binding site | 159-169 | substrate | |||
Binding site | 164 | substrate | |||
Binding site | 182 | substrate | |||
Binding site | 183 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | orotidine-5'-phosphate decarboxylase activity | |
Biological Process | 'de novo' pyrimidine nucleobase biosynthetic process | |
Biological Process | 'de novo' UMP biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameOrotidine 5'-phosphate decarboxylase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageArchaea > Thermoproteota > Thermoprotei > Sulfolobales > Sulfolobaceae > Sulfolobus
Accessions
- Primary accessionA0A550D551
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Subunit
Homodimer.
Structure
Sequence
- Sequence statusComplete
- Length209
- Mass (Da)23,544
- Last updated2019-10-16 v1
- Checksum2BD662BC5DFCB5A5
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
QFWC01000012 EMBL· GenBank· DDBJ | TRM85329.1 EMBL· GenBank· DDBJ | Genomic DNA |