A0A536AEK4 · A0A536AEK4_UNCCH

  • Protein
    Putative [LysW]-L-2-aminoadipate 6-phosphate reductase
  • Gene
    lysY
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the NADPH-dependent reduction of [LysW]-aminoadipate 6-phosphate to yield [LysW]-aminoadipate 6-semialdehyde.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-lysine from L-alpha-aminoadipate (Thermus route): step 3/5.

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site144
Binding site312NADP+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionN-acetyl-gamma-aminoadipyl-phosphate reductase activity
Molecular FunctionN-acetyl-gamma-glutamyl-phosphate reductase activity
Molecular FunctionNAD binding
Molecular FunctionNADP+ binding
Biological Processarginine biosynthetic process
Biological Processlysine biosynthetic process via aminoadipic acid

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Putative [LysW]-L-2-aminoadipate 6-phosphate reductase
  • EC number

Gene names

    • Name
      lysY
    • ORF names
      E6I51_00445

Organism names

Accessions

  • Primary accession
    A0A536AEK4

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain2-136Semialdehyde dehydrogenase NAD-binding
Region175-194Disordered
Compositional bias178-194Basic and acidic residues

Sequence similarities

Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    344
  • Mass (Da)
    37,218
  • Last updated
    2019-10-16 v1
  • Checksum
    5510B898C44ACDFB
MKVGIVGAAGYAGGELLRLLLGHPEVGEIVAGSESLAGKPVSAAHPNLRKRTSLSFVHYEDVTKCDVLFLSLPNGAHRAHEFEDRATVLVDLSSDHRLRDPSDYDRWYGSPHPHPDRLDRFVYGIPELRRAAIKGAKRITGAGCNATASILALLPLFQADVVDRARPVVIECKVGSSEGGREPSEDSHHPERSGVVRSFRPVGHRHTAEIEQELALGADPPRVDLSVTSVELVRGVLATAHVYTKDALDEKELWRIYRGAYASEPFVRIVKERTGIYRYPEPKLLAGTNFADVGFALDARANRVVALCAIDNLVKGAAGNGVQAMNVSCGFAEDAGLGFLGLHP

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias178-194Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VBGF01000008
EMBL· GenBank· DDBJ
TME65397.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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