A0A518BIJ0 · A0A518BIJ0_9BACT

Function

function

Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site178Nucleophile
Active site240

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionL-methionine:thioredoxin-disulfide S-oxidoreductase activity
Molecular Functionpeptide-methionine (R)-S-oxide reductase activity
Molecular Functionpeptide-methionine (S)-S-oxide reductase activity
Biological Processprotein modification process
Biological Processprotein repair
Biological Processresponse to oxidative stress

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Multifunctional fusion protein

Including 2 domains:

  • Recommended name
    Peptide methionine sulfoxide reductase MsrA
  • EC number
  • Short names
    Protein-methionine-S-oxide reductase
  • Alternative names
    • Peptide-methionine (S)-S-oxide reductase
      (Peptide Met(O) reductase
      )
  • Recommended name
    Peptide methionine sulfoxide reductase MsrB
  • EC number
  • Alternative names
    • Peptide-methionine (R)-S-oxide reductase

Gene names

    • Name
      msrA3
    • Synonyms
      msrA
      , msrB
    • ORF names
      Pla133_18390

Organism names

Accessions

  • Primary accession
    A0A518BIJ0

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-21
ChainPRO_502178271422-396Multifunctional fusion protein

Family & Domains

Features

Showing features for region, domain.

Type
IDPosition(s)Description
Region40-62Disordered
Domain66-189MsrB

Sequence similarities

Belongs to the MsrA Met sulfoxide reductase family.
Belongs to the MsrB Met sulfoxide reductase family.
In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    396
  • Mass (Da)
    43,288
  • Last updated
    2019-10-16 v1
  • Checksum
    C91CA3DB02A233C2
MLTTRLLAALAPIALTLAACVNQSDGTSGVAIGGTASGNAAGGVSEASPGESDAPTRPGEFVKPSDQELRELLTDEQYRVTQQSGTERAFSGEYDKFWEPGIYVDVVSGEPLFSSLDKFNSGTGWPSFTRPIEAESVVELEDRDGRWVRTEIRSAKADSHLGHVFPDGPREAGGMRYCMNSAALRFVPLDELGRRGYDEYLGRFEAAGLVPAADSATDQQATGEQAMGEQTEKAIIAGGCFWGMEELLRKIDGVLDTEVGYCGGSNADATYRNHPGHAEAVLVTFDPSKISFERLLTDWFFRMHDPTTLDRQGNDRGSSYRSTIFYFDAEQKRVAEDAIAEVGASGKWSDPIVTTVEPVKNWSVAEPEHQDYLASRPNGYTCHFLRPWDEGVTNQR

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP036287
EMBL· GenBank· DDBJ
QDU66763.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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