A0A517ME10 · A0A517ME10_9BACT

  • Protein
    Sulfate adenylyltransferase subunit 1
  • Gene
    cysNC_2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

function

APS kinase catalyzes the synthesis of activated sulfate.
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

Catalytic activity

Pathway

Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3.

Features

Showing features for binding site.

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TypeIDPosition(s)Description
Binding site31-38GTP (UniProtKB | ChEBI)
Binding site110-114GTP (UniProtKB | ChEBI)
Binding site165-168GTP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionadenylylsulfate kinase activity
Molecular FunctionATP binding
Molecular FunctionGTP binding
Molecular FunctionGTPase activity
Molecular Functionsulfate adenylyltransferase (ATP) activity
Biological Processhydrogen sulfide biosynthetic process
Biological Processsulfate assimilation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Sulfate adenylyltransferase subunit 1
  • EC number
  • Alternative names
    • ATP-sulfurylase large subunit
    • Sulfate adenylate transferase
      (SAT
      )

Gene names

    • Name
      cysNC_2
    • Synonyms
      cysN
    • ORF names
      FF011L_18770

Organism names

  • Taxonomic identifier
  • Strain
    • FF011L
  • Taxonomic lineage
    Bacteria > Planctomycetota > Planctomycetia > Pirellulales > Pirellulaceae > Roseimaritima

Accessions

  • Primary accession
    A0A517ME10

Proteomes

Interaction

Subunit

Heterodimer composed of CysD, the smaller subunit, and CysN.

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain22-237Tr-type G
Region447-469Disordered

Sequence similarities

In the C-terminal section; belongs to the APS kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    647
  • Mass (Da)
    71,037
  • Last updated
    2019-10-16 v1
  • Checksum
    9124FC0CE5EB10A2
MSHQSDLIATDIDAYLKQHEHKQLLRFITCGSVDDGKSTLIGRLLFDSKMLYEDELSKIESDSVTQGSAGGKFDPALATDGLKEEREQGITIDVAYRYFSTAKRKFIIADTPGHEQYTRNMATGASTADLAVILIDARHGVLTQTRRHSFIVSLLGIRHVVVAVNKMDLVDFSEERFEEICRDYRAFAARLDLPDLHFIPISALNGDNVVDESPSTPWYTGSTLMNFLESVYIGSDRNLRDFRMPVQYVNRPNLDFRGFCGTIASGIIRTGEPVTILPSQQTSKIKSIETFAGPIDEAYAPLAVTLTLEDEIDASRGDMIVRSGNIPRSSDSINAMVVWMNQDPMLPGKTYLFKHTTQTLPGSIETLNYKIDVNTLHRSPTPQLALNEIGRVSVSLNHPIHFDAYRRNHNTGSFIIIDRLTNATVGAGMILDGTTDPKHTAIWDDETSEATGSDDGSVPNVGSEEREARFGQKPATILLTGLTGSGKSTVASACERKLFDSGRAVAVIDGERVRAGLSRDLGFSAKDRSENLRRSAFLAQTLNDAGILCIAAFVAPNESVRQKAASVVGNDRFLVVHVATPLETCRERDTKGQYAQADAGKLQDFPGVTAPYEVPDAADLVINPAEDSLDDCVSAILELLREKEFIR

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP036262
EMBL· GenBank· DDBJ
QDS93122.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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