A0A517M9C6 · A0A517M9C6_9BACT
- ProteinUridylate kinase
- GenepyrH
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids257 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reversible phosphorylation of UMP to UDP.
Catalytic activity
- ATP + UMP = ADP + UDP
Activity regulation
Inhibited by UTP.
Pathway
Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 25-28 | ATP (UniProtKB | ChEBI) | ||||
Sequence: KLSG | ||||||
Binding site | 67 | UMP (UniProtKB | ChEBI) | ||||
Sequence: G | ||||||
Binding site | 68 | ATP (UniProtKB | ChEBI) | ||||
Sequence: G | ||||||
Binding site | 72 | ATP (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 150-157 | UMP (UniProtKB | ChEBI) | ||||
Sequence: IGSPFVTT | ||||||
Binding site | 177 | ATP (UniProtKB | ChEBI) | ||||
Sequence: T | ||||||
Binding site | 183 | ATP (UniProtKB | ChEBI) | ||||
Sequence: Y | ||||||
Binding site | 186 | ATP (UniProtKB | ChEBI) | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | UMP kinase activity | |
Biological Process | 'de novo' CTP biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUridylate kinase
- EC number
- Short namesUK
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Planctomycetota > Planctomycetia > Pirellulales > Pirellulaceae > Roseimaritima
Accessions
- Primary accessionA0A517M9C6
Proteomes
Subcellular Location
Interaction
Subunit
Homohexamer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 20-231 | Aspartate/glutamate/uridylate kinase | ||||
Sequence: KRVILKLSGESLSASGDRGIGAVEVAHIAAQIRSALDSGCQIAVVIGGGNILRGAQFSGRNNNVQEATAHYMGMLATTINALALQDALESAGCQTRVMSALEMDTVCERFIRRRALRHLEKGRVVVLAAGIGSPFVTTDTAAAQRALELNADVVLKATRVDGVYSEDPEKNPHAVMYESLSYAEVIEKNLRVMDGTAIALCREHSTPILVFN |
Sequence similarities
Belongs to the UMP kinase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length257
- Mass (Da)27,231
- Last updated2019-10-16 v1
- Checksum25A2EAAA5F08D6A8
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP036262 EMBL· GenBank· DDBJ | QDS91479.1 EMBL· GenBank· DDBJ | Genomic DNA |