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A0A517D5D1 · A0A517D5D1_LIMRT

Function

function

Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO2 group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Pathway

Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site40Zn2+ (UniProtKB | ChEBI)
Binding site43Zn2+ (UniProtKB | ChEBI)
Binding site58Zn2+ (UniProtKB | ChEBI)
Binding site61Zn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentacetyl-CoA carboxylase complex
Molecular Functionacetyl-CoA carboxylase activity
Molecular FunctionATP binding
Molecular Functioncarboxyl- or carbamoyltransferase activity
Molecular Functionzinc ion binding
Biological Processfatty acid biosynthetic process
Biological Processmalonyl-CoA biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
  • EC number
  • Short names
    ACCase subunit beta
    ; Acetyl-CoA carboxylase carboxyltransferase subunit beta

Gene names

    • Name
      accD
    • ORF names
      FOD75_04715

Organism names

Accessions

  • Primary accession
    A0A517D5D1

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain36-292CoA carboxyltransferase N-terminal

Sequence similarities

Belongs to the AccD/PCCB family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    292
  • Mass (Da)
    32,712
  • Last updated
    2019-10-16 v1
  • MD5 Checksum
    E68A60357511AC15CE0835BCBD341D2D
MEEGADSVKLYDQNNTLSERHIKADKNADERVPDQMWLRCPHCHQLLFAKQLTQYAVCPDCDYGLRMPARHRLSWLVDSFKEFDGDLQTKDPLHFPGYQEKVSKLQRQTKLNDSVLTGLTGEASINNQLFSLGIMDPTFIMGSLGTVTVEKITRLFEYATTHRQAVVLFTASGGARMQEGIMSLMQMAKVSQAINEHAVADLLYIVVLTDPTTGGVTASFAMDGDIILAEPHALVGFAGRRVIEQTIHQQIPVDLQSAENILNHGFIDRIVKRQDEKQLLEWLLKTGSVANE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP041676
EMBL· GenBank· DDBJ
QDR72437.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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