A0A510PI38 · A0A510PI38_MICAE

Function

function

Catalyzes the conversion of lactate to pyruvate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Activity regulation

Allosterically activated by fructose 1,6-bisphosphate (FBP).

Pathway

Fermentation; pyruvate fermentation to lactate; (S)-lactate from pyruvate: step 1/1.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site27-32NAD+ (UniProtKB | ChEBI)
Binding site31NAD+ (UniProtKB | ChEBI)
Binding site52NAD+ (UniProtKB | ChEBI)
Binding site57NAD+ (UniProtKB | ChEBI)
Binding site97-98NAD+ (UniProtKB | ChEBI)
Binding site100substrate
Binding site106substrate
Binding site113NAD+ (UniProtKB | ChEBI)
Binding site136-138NAD+ (UniProtKB | ChEBI)
Binding site138-141substrate
Binding site161NAD+ (UniProtKB | ChEBI)
Binding site166-169substrate
Binding site171beta-D-fructose 1,6-bisphosphate (UniProtKB | ChEBI); allosteric activator
Binding site186beta-D-fructose 1,6-bisphosphate (UniProtKB | ChEBI); allosteric activator
Active site193Proton acceptor
Binding site248substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionL-lactate dehydrogenase activity
Biological Processglycolytic process
Biological Processlactate metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    L-lactate dehydrogenase
  • EC number
  • Short names
    L-LDH

Gene names

    • Name
      ldh
    • ORF names
      MAE30S32_20510

Organism names

  • Taxonomic identifier
  • Strain
    • 11-30S32
  • Taxonomic lineage
    Bacteria > Cyanobacteriota > Cyanophyceae > Oscillatoriophycideae > Chroococcales > Microcystaceae > Microcystis

Accessions

  • Primary accession
    A0A510PI38

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue239Phosphotyrosine

Keywords

Interaction

Subunit

Homotetramer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain24-160Lactate/malate dehydrogenase N-terminal
Domain163-328Lactate/malate dehydrogenase C-terminal

Sequence similarities

Belongs to the LDH/MDH superfamily. LDH family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    331
  • Mass (Da)
    36,392
  • Last updated
    2019-10-16 v1
  • Checksum
    FBCEA10A5DE79000
MLDKIFTPNPYAEKPAPLRPRKGVIIGVGQVGMACAYSMLIQDCFDELILQDIATDKVEGEVMDLRHGMPFIEPTDLKMGTVADVGQNADVVIITAGAAQKEGETRLHLLERNVAIFRRILEDVAVYCPSALILVVSNPVDIMTYVTLKITNFPPSRVIGSGTVLDSARLRSLLSTQLHVDARNVHAYIIGEHGDSELAVWSSANIGGARLLERDWQDLSAADQESLTEIFLQVKNAAYEIIKRKGYTSYAIGLATTDIVKAILRSQERILTISTLLDGQYGLKDVCLSIPSVVNEKGVIKTLNLALSPRETQQLHNSAKIMRDLIDQLKI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BHVU01000105
EMBL· GenBank· DDBJ
GCA93399.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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