A0A4Y9QPH2 · A0A4Y9QPH2_9BACT
- ProteinCatalase-peroxidase
- GenekatG
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids759 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
Catalytic activity
- 2 H2O2 = 2 H2O + O2
Cofactor
Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
Features
Showing features for site, active site, binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | catalase activity | |
Molecular Function | heme binding | |
Molecular Function | metal ion binding | |
Biological Process | cellular response to hydrogen peroxide | |
Biological Process | hydrogen peroxide catabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCatalase-peroxidase
- EC number
- Short namesCP
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacteroidota > Cytophagia > Cytophagales > Cyclobacteriaceae > Algoriphagus
Accessions
- Primary accessionA0A4Y9QPH2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for signal, chain, cross-link.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-20 | |||||
Sequence: MLKRILALALILGSLTSVNA | ||||||
Chain | PRO_5021453288 | 21-759 | Catalase-peroxidase | |||
Sequence: QEKYTEGAPVDAYTGATKKSSTAMRATSNTDWWPNQLNLSILRQNSELSNPMDPDFDYIKAFNSLEYEALKSDLRALMTDSQDWWPADFGHYGGLFIRMAWHSAGTYRSGDGRGGSRSGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGDKISWADLMVLTGNVALESMGFETYGFAGGREDVYEPELDVYWGAEGKWLDDSKRYSEGRKLENPLAAVQMGLIYVNPEGPNGNPDPVLAAHDIRETFGRMGMNDEETVALIAGGHTLGKTHGAGPADNVGPEPEAAPIEEQGLGWKSSYKSGKGADAITSGLEVIWTLTPTEWSQGFFKSLFENEWELTKSPAGAHQWVAKNPEVLYPDAFDSTKKHKPTMLTTDLSMRFDPVYEKISRRFYENPEEFNKAFAKAWFKLTHRDMGPKTTYLGPEAPTEDLIWQDPIPALNHEVVNAQDIEKLKSEILNSGLSISELVTTAWASASTYRHSDRRGGANGARIMLAPQRNWEVNNPAQLNKVLGVLEGIQTKFNSAQSGNKKVSMADLIVLAGTAAVEKAAHNAGYTDVEVEFTPGRMDALQEQTDVQSFNLLEPMADGFRNYLKTQYTLSTEELLVDKAQLLRLTAPEMTVLVGGMRALHANYDGSNHGIFTDKQDQLTNDFFVNLLDMSTEWKAVDDTKEIFEGRDRKTGEVKYTATRADLIFGSNSELRALAEVYGQFDNEEKFVHDFVNAWTKVMNLDRFDLTYQK | ||||||
Cross-link | 245↔271 | Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-121) | ||||
Sequence: YVNPEGPNGNPDPVLAAHDIRETFGRM |
Post-translational modification
Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
Interaction
Subunit
Homodimer or homotetramer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 155-443 | Plant heme peroxidase family profile | ||||
Sequence: LDKARRLLWPIKQKYGDKISWADLMVLTGNVALESMGFETYGFAGGREDVYEPELDVYWGAEGKWLDDSKRYSEGRKLENPLAAVQMGLIYVNPEGPNGNPDPVLAAHDIRETFGRMGMNDEETVALIAGGHTLGKTHGAGPADNVGPEPEAAPIEEQGLGWKSSYKSGKGADAITSGLEVIWTLTPTEWSQGFFKSLFENEWELTKSPAGAHQWVAKNPEVLYPDAFDSTKKHKPTMLTTDLSMRFDPVYEKISRRFYENPEEFNKAFAKAWFKLTHRDMGPKTTYLG |
Sequence similarities
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length759
- Mass (Da)84,774
- Last updated2019-09-18 v1
- ChecksumE1F996ECA9CEC61B
Keywords
- Technical term