A0A4Y9EJN8 · A0A4Y9EJN8_9SPHN

Function

function

Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.

Pathway

Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrin-IX from protoporphyrinogen-IX: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site16Fe (UniProtKB | ChEBI) of heme (UniProtKB | ChEBI); axial binding residue
Binding site90Fe (UniProtKB | ChEBI) of heme (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionmetal ion binding
Molecular Functionprotoporphyrinogen oxidase activity
Biological Processprotoporphyrinogen IX biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Protoporphyrinogen IX oxidase
  • EC number
  • Short names
    PPO

Gene names

    • ORF names
      EUV02_14810

Organism names

  • Taxonomic identifier
  • Strain
    • DJ1R-1
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Sphingomonadales > Sphingosinicellaceae > Polymorphobacter

Accessions

  • Primary accession
    A0A4Y9EJN8

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-30Helical
Transmembrane61-80Helical
Transmembrane86-105Helical
Transmembrane125-143Helical

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the HemJ family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    146
  • Mass (Da)
    16,621
  • Last updated
    2019-09-18 v1
  • Checksum
    F5DC8AC5FA065AE4
MIGWLGGAYLWVKAFHVIFVIFWMAGLFILPRYLVHHTATVPGSPEDAEWIKREMLLRRMILNPASILTWALGLCLAGSLGFDYPWLWAKFGFVVLLTGYDHWAVATSKKLARGLRPYAERRLRMLNEVPALLIIAIVIMVVVKPS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
SIHO01000004
EMBL· GenBank· DDBJ
TFU00322.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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