A0A4Y7U5Z1 · A0A4Y7U5Z1_9FLAO
- Proteinhomoserine dehydrogenase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids178 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
Catalytic activity
- L-homoserine + NADP+ = H+ + L-aspartate 4-semialdehyde + NADPHThis reaction proceeds in the backward direction.
Cofactor
Pathway
Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 3/3.
Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 3/5.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | homoserine dehydrogenase activity | |
Molecular Function | kinase activity | |
Molecular Function | NADP binding | |
Biological Process | homoserine biosynthetic process | |
Biological Process | threonine biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namehomoserine dehydrogenase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacteroidota > Flavobacteriia > Flavobacteriales > Flavobacteriaceae > Flavobacterium
Accessions
- Primary accessionA0A4Y7U5Z1
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 21-110 | Aspartate/homoserine dehydrogenase NAD-binding | ||||
Sequence: VGYAWETNFVQLAVPFRVEDIVEFAKENEFENLIAVDATASDELISHYNTLIQNGFNIVAVNKKANTLPIGLYKEIRENLKKYDKEFLYE | ||||||
Domain | 118-178 | Homoserine dehydrogenase catalytic | ||||
Sequence: PVLQTLRDLYNSGEKITKIRGVFSDNLSYVFNRFSSDETAFSAVLKDASLLGFMRSTFRED |
Family and domain databases
Sequence
- Sequence statusFragment
- Length178
- Mass (Da)20,356
- Last updated2019-09-18 v1
- Checksum0E7554580B01B2AA
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: I | ||||||
Non-terminal residue | 178 | |||||
Sequence: D |