A0A4Y7RAF8 · A0A4Y7RAF8_9FIRM
- ProteinDNA polymerase beta
- GenepolX
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids567 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
Catalytic activity
- 2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H+
- a 5'-end 2'-deoxyribose-2'-deoxyribonucleotide-DNA = (2E,4S)-4-hydroxypenten-2-al-5-phosphate + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H+
Cofactor
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | DNA binding | |
Molecular Function | DNA-directed DNA polymerase activity | |
Molecular Function | exonuclease activity | |
Molecular Function | phosphoric ester hydrolase activity | |
Molecular Function | zinc ion binding | |
Biological Process | bacterial-type flagellum-dependent swarming motility | |
Biological Process | DNA repair |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA polymerase beta
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Clostridia > Eubacteriales > Desulfotomaculaceae > Pelotomaculum
Accessions
- Primary accessionA0A4Y7RAF8
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-310 | DNA-directed DNA polymerase X | ||||
Sequence: MQNEEIAWIFHELADLLELKGEEYFKIRAYRNASRILAGLDEPVKDAWKGGRLNKIPGIGKNIAAKINELLTTGNLKKYQELLEEFPPGLLAIITLPGLGPKKAGMIREKLGITSLEELAAAAREKRLRNLPGLGVRTEDEILRNIELRQSQAGRALLDLARNIAAELKGYLELLPGVARVEAGGSLRRWKETVGDIDLVVASDDPNTVIDSLAGHYRISHILEKGYDGAKFQTKWGIAVELEIVPEEVFTLALFRNTGSHAHFEKLQGLFEKKENSAAAALLGRNRGEMAEQDIYAMLDLQYIPPELRE | ||||||
Domain | 51-70 | Helix-hairpin-helix DNA-binding motif class 1 | ||||
Sequence: GRLNKIPGIGKNIAAKINEL | ||||||
Domain | 91-110 | Helix-hairpin-helix DNA-binding motif class 1 | ||||
Sequence: LAIITLPGLGPKKAGMIREK | ||||||
Domain | 126-145 | Helix-hairpin-helix DNA-binding motif class 1 | ||||
Sequence: KRLRNLPGLGVRTEDEILRN | ||||||
Domain | 334-413 | Polymerase/histidinol phosphatase N-terminal | ||||
Sequence: GDLHVHSTWSDGVADIEQLAGRAKAKGYQYMAVTDHSRSLHIARGLSLDKLHEQHEVIRELNKKQEDFRILTGIEVDILP |
Family and domain databases
Sequence
- Sequence statusComplete
- Length567
- Mass (Da)63,373
- Last updated2019-09-18 v1
- ChecksumB7FABC571D0ACFE4
Keywords
- Technical term