A0A4Y6UT54 · A0A4Y6UT54_SACBS

  • Protein
    Glycerol-3-phosphate dehydrogenase [NAD(P)+]
  • Gene
    gpsA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

function

Catalyzes the reduction of the glycolytic intermediate dihydroxyacetone phosphate (DHAP) to sn-glycerol 3-phosphate (G3P), the key precursor for phospholipid synthesis.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Pathway

Membrane lipid metabolism; glycerophospholipid metabolism.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site12NADPH (UniProtKB | ChEBI)
Binding site13NADPH (UniProtKB | ChEBI)
Binding site33NADPH (UniProtKB | ChEBI)
Binding site107NADPH (UniProtKB | ChEBI)
Binding site107sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site107substrate
Binding site137sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site139sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site141NAD+ (UniProtKB | ChEBI)
Binding site141NADPH (UniProtKB | ChEBI)
Active site192Proton acceptor
Binding site192sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site245sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site255sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site256NAD+ (UniProtKB | ChEBI)
Binding site256NADPH (UniProtKB | ChEBI)
Binding site256sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site256-257substrate
Binding site257sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site280NADPH (UniProtKB | ChEBI)
Binding site282NADPH (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionglycerol-3-phosphate dehydrogenase (NADP+) activity
Molecular Functionglycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Molecular FunctionNAD binding
Biological Processcarbohydrate metabolic process
Biological Processglycerol-3-phosphate biosynthetic process
Biological Processglycerol-3-phosphate catabolic process
Biological Processglycerophospholipid metabolic process
Biological Processphospholipid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glycerol-3-phosphate dehydrogenase [NAD(P)+]
  • EC number
  • Alternative names
    • NAD(P)(+)-dependent glycerol-3-phosphate dehydrogenase
    • NAD(P)H-dependent dihydroxyacetone-phosphate reductase

Gene names

    • Name
      gpsA
    • ORF names
      FFV09_00790

Organism names

  • Taxonomic identifier
  • Strain
    • KCTC 43072 / ATSA2
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Bacillales > Paenibacillaceae > Saccharibacillus

Accessions

  • Primary accession
    A0A4Y6UT54

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-18
ChainPRO_503874298019-346Glycerol-3-phosphate dehydrogenase [NAD(P)+]

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain4-160Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Domain181-322Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    346
  • Mass (Da)
    37,767
  • Last updated
    2019-09-18 v1
  • Checksum
    67EA74FF2C49259C
MAKKVCVLVAGSWGTALAMVLADNGHDVRLWARSEEHVQEINETRENSRFLPGVKLPDGLRATSDMQDALSEAEAVIIASPSKAMREVARALKPFWNEDMLCVHATKGMETGTLKRMSTIIAEELGCEESKIGVICGPSHAEEVARRRPTTIVVASANEGEAQRAQNLLMNAYFRVYTNRDVLGAELAGAFKNIIALGAGMSDGLEYGDNAKAALLTRGLAEITRIGTEMGANPLTFSGLAGVGDLVVTATSKHSRNWRAGYMIGQGKPLQEVLDSMGMVVEGIRTTEAAHFISQKYKVQMPIAEQLYRVLFEDLDPKTAVEALMGRGPKTEMEMISQETWEQWHT

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP041217
EMBL· GenBank· DDBJ
QDH19517.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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