A0A4X2L7Q2 · A0A4X2L7Q2_VOMUR

Function

Catalytic activity

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site94ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcentriolar satellite
Cellular Componentcentriole
Cellular Componentchromatin
Cellular Componentmidbody
Cellular Componentmitotic spindle pole
Cellular Componentouter kinetochore
Cellular Componentspindle microtubule
Cellular Componentspindle midzone
Cellular Componentsynaptonemal complex
Molecular Functionanaphase-promoting complex binding
Molecular FunctionATP binding
Molecular Functionidentical protein binding
Molecular Functionmagnesium ion binding
Molecular Functionmicrotubule binding
Molecular Functionprotein kinase binding
Molecular Functionprotein serine kinase activity
Molecular Functionprotein serine/threonine kinase activity
Biological Processcentrosome cycle
Biological Processdouble-strand break repair via alternative nonhomologous end joining
Biological Processestablishment of mitotic spindle orientation
Biological Processestablishment of protein localization
Biological Processfemale meiosis chromosome segregation
Biological ProcessG2/M transition of mitotic cell cycle
Biological Processhomologous chromosome segregation
Biological Processmicrotubule bundle formation
Biological Processmitotic cytokinesis
Biological Processmitotic G2 DNA damage checkpoint signaling
Biological Processmitotic sister chromatid segregation
Biological Processmitotic spindle assembly checkpoint signaling
Biological Processnegative regulation of apoptotic process
Biological Processnegative regulation of double-strand break repair via homologous recombination
Biological Processnegative regulation of transcription by RNA polymerase II
Biological Processnuclear membrane disassembly
Biological Processpositive regulation of peptidyl-threonine phosphorylation
Biological Processpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
Biological Processprotein destabilization
Biological Processprotein localization to chromatin
Biological Processprotein localization to nuclear envelope
Biological Processprotein ubiquitination
Biological Processregulation of cytokinesis
Biological Processregulation of mitotic spindle assembly
Biological Processregulation of protein localization to cell cortex
Biological Processsynaptonemal complex disassembly

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Serine/threonine-protein kinase PLK
  • EC number
  • Alternative names
    • Polo-like kinase

Gene names

    • Name
      PLK1

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Metatheria > Diprotodontia > Vombatidae > Vombatus

Accessions

  • Primary accession
    A0A4X2L7Q2

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region1-53Disordered
Domain65-317Protein kinase
Domain421-499POLO box
Domain521-603POLO box

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    615
  • Mass (Da)
    68,980
  • Last updated
    2019-09-18 v1
  • Checksum
    350BDAFFEFE695CC
MSAAPAKLPLRQPGVGSSEPRGKPAVGGGGAGTGAGAGGGTTTVPPAAAPEIPEVLVDPRSRRRYLRGRFLGKGGFAKCFELSDLESKEVFAGKIVPKSLLLKPHQKEKMSMEINIHKSLVHQHVVGFHGFFEDSDFVFVVLELCRRRSLLELHKRRKAVTEPEARYYLRQIVLGCQYLHENKVIHRDLKLGNLFLNDDMEVKIGDFGLATRVEYDGERKRTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYIRIKKNEYSIPKHINPVAASLIQKMLRSDPASRPTINELLNDEFFSSGYIPSRLPTTCLTIPPRFSIAPNSVESGGRKPLTALNKGMDNPAPEQPPEKEVIVQEPNGPADCYLSDMLQQLLSVNAAKPSDRRLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIEQNGSESYLTVRSYPSSLTKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGTVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYKLSLLEEHGCCKELASRLRYARTMVDKLLSSRSASARLKSST

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A4X2LAP1A0A4X2LAP1_VOMURPLK1585
A0A4X2L8R3A0A4X2L8R3_VOMURPLK1598
A0A4X2L8S7A0A4X2L8S7_VOMURPLK1183

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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