A0A4X2KHE4 · A0A4X2KHE4_VOMUR

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentapical plasma membrane
Cellular Componentapicolateral plasma membrane
Cellular Componentcell surface
Cellular Componentcytoplasmic vesicle membrane
Cellular Componentendoplasmic reticulum membrane
Molecular FunctionG protein-coupled receptor activity
Molecular Functionubiquitin protein ligase binding
Molecular FunctionWnt receptor activity
Molecular FunctionWnt-protein binding
Biological Processcell proliferation in midbrain
Biological Processembryonic nail plate morphogenesis
Biological Processestablishment of body hair planar orientation
Biological Processhair follicle development
Biological Processinner ear morphogenesis
Biological Processnegative regulation of canonical Wnt signaling pathway
Biological Processneural tube closure
Biological Processplatelet activation
Biological ProcessWnt signaling pathway, planar cell polarity pathway

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Frizzled-6

Gene names

    • Name
      FZD6

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Metatheria > Diprotodontia > Vombatidae > Vombatus

Accessions

  • Primary accession
    A0A4X2KHE4

Proteomes

Subcellular Location

Apical cell membrane
; Multi-pass membrane protein
Cell membrane
; Multi-pass membrane protein
Cell surface
Cytoplasmic vesicle membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane201-222Helical
Transmembrane234-254Helical
Transmembrane284-312Helical
Transmembrane324-345Helical
Transmembrane369-393Helical
Transmembrane413-438Helical
Transmembrane473-494Helical

Keywords

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

TypeIDPosition(s)Description
Signal1-18
ChainPRO_502133936119-712Frizzled-6
Disulfide bond24↔85
Disulfide bond32↔78
Disulfide bond99↔123

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain19-132FZ
Domain195-502G-protein coupled receptors family 2 profile 2
Region588-654Disordered
Compositional bias607-628Polar residues
Region669-712Disordered

Sequence similarities

Belongs to the G-protein coupled receptor Fz/Smo family.

Keywords

Phylogenomic databases

Family and domain databases

Protein family/group databases

Sequence

  • Sequence status
    Complete
  • Length
    712
  • Mass (Da)
    80,150
  • Last updated
    2019-09-18 v1
  • Checksum
    82FE2AC9BEBD40D9
METVLFFVMCITLPLIRGHSFFTCEPITVPKCVKMTYNMTFFPNLMGHYDQSIAALEMEPFLPLANLHCSPDVDTFLCNAFVPACTEQIHVVPPCRKFCERVYSDCKYLIDTFGITWPEELECSRLQYCDETAPVASDLTTKFHDPPKTPQQVQRDYGFWCPRHLKTSGGQGYKFLGIDQCAPPCPNMYFKNDELEFAKSFIGIVSIFCLCATLFTFLTFLIDVKRFRYPERPIIYYSVCYSIVSLMYFIGFLLGNSTACNKADEKLELGETVVLGSQNKACTVLFMLLYFFTMAGTVWWVILTITWFLAAGRKWSCEAIEQKAVWFHAVAWGMPGFLTVMLLAMNKVEGDNISGVCFVGLYDLYASRYFVLLPLCLCVFVGLSLLLAGIISLNHVRQVIQHDGRNQEKLKKFMIRIGVFSGLYLVPLVTLLGCYVYEQIYRIIWETTWVSDHCHRYHIPCPHQAKTLARPELALFMIKYLMTLIVGISAVFWVGSKKTCTEWASFFNRNRKRDPISESRRVLQESCEFFLKHNSKVKHKKKHYKSSSHKLKVISKSMGTSTGATANHGTSAVAIANHDCLGQENLTEIKTSPEASVRDMGADGSSLQKARENNVGEHTSPADSSSKLSVEQVERRCKTGNSNDKSSVSGSVWSEGRVTPKANFTETHLLQSSNLQIPSTSQPGSPKGSTSLLIHSTLDTGKEQSSGNNSDT

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias607-628Polar residues

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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