A0A4W6BRP6 · A0A4W6BRP6_LATCA

Function

Features

Showing features for binding site.

1893100200300400500600700800
TypeIDPosition(s)Description
Binding site699Ca2+ (UniProtKB | ChEBI)
Binding site701Ca2+ (UniProtKB | ChEBI)
Binding site703Ca2+ (UniProtKB | ChEBI)
Binding site705Ca2+ (UniProtKB | ChEBI)
Binding site710Ca2+ (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcell projection
Cellular Componentcytoplasmic vesicle membrane
Cellular Componentendoplasmic reticulum
Cellular Componentmonoatomic ion channel complex
Cellular Componentplasma membrane
Molecular Functioncalcium ion binding
Molecular Functionmuscle alpha-actinin binding
Molecular Functionpotassium channel activity
Molecular Functionsignaling receptor binding
Molecular Functionvoltage-gated calcium channel activity
Molecular Functionvoltage-gated sodium channel activity
Biological Processdetection of mechanical stimulus
Biological Processrelease of sequestered calcium ion into cytosol
Biological ProcessWnt signaling pathway

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Polycystin-2

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Carangaria > Carangaria incertae sedis > Centropomidae > Lates

Accessions

  • Primary accession
    A0A4W6BRP6

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Cytoplasmic vesicle membrane
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane166-190Helical
Transmembrane413-430Helical
Transmembrane451-473Helical
Transmembrane493-512Helical
Transmembrane532-554Helical

Keywords

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond272↔285

Keywords

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region1-128Disordered
Compositional bias79-103Polar residues
Domain686-721EF-hand
Compositional bias706-730Basic and acidic residues
Region706-770Disordered
Region850-893Disordered

Sequence similarities

Belongs to the polycystin family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    893
  • Mass (Da)
    101,712
  • Last updated
    2019-09-18 v1
  • Checksum
    E15F0B0B5B955D4C
MSSSRVRPQQVPQTGRLPHRLDSTEGIEMENIQHQDLGLGGVAGTPSPPSRQAWSRDNPGFEPEDEIMEADWPPASPGRRSVSTASSSSCSSGLGSYTGPGSSTHIPRGGLYPTPTLDQQQQERPEQPGCLKQILHRLRVLWGTELMEDSDSSRERYLRNVLREMITYITFLITICILTYGMVSANMYYYTRVMSQLFLDSPLSAEDSSTFRHLSTMEDFWKFTEGPFLSGMYWEVWYNNKSLPENQSLIYYENLLLGVPRLRQVRVRNESCSVHEDLRDEVQDCYDMYTPANEDTAPFGPRNGTAWVYTTESEMNSSSFWGQVSKYGGGGYYQDLSRTREESAIQLQVLKDHLWLDRGTRAVFLDFSVYNGNINLFCIARLLVEFPATGGVVTSWQFQTVRLVRYVSSWDCFVGMCEVAFCLFVLYYVVEEVLEIRIHRLHYFKSLWNCLDVLILVVCIRVELGVIEVLNSLLENHTAHPSFEPLSDLQVQFNNVAAVIVFFSWVKLFKFINFNKTMSQLSSTMSRCAKDLVGFTIMFFIIFLAYAQLAYLVFGTQVNDFSTFQASIFTQFRIILGDFEFSEIEEAKPGASDRSTSPPLTHRLFVSVQNMFLAIINDTYSEVKADMSQQRSDMEMTDLIKKGCNKALMKLRLKKTAVDDISDSLRQAGGKLNFDELRQDLKGKGHTDAEIQAIFAKYDQDGDQELTEHEHQQMRDDLEKEREDLDLERNSLTRPSSGRSFPRTQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERVKLKRRDVVGRLLDGVMEDERLGRDTDVHREQMERLVREEMERWESDDMVSQVSHPQPPTPVGPRPRPPSSLSADGLDAGTNGSG

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A4W6BWJ5A0A4W6BWJ5_LATCA903
A0A4W6BZI6A0A4W6BZI6_LATCA895

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias79-103Polar residues
Compositional bias706-730Basic and acidic residues

Keywords

Genome annotation databases

Similar Proteins

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