A0A4W4GHH1 · A0A4W4GHH1_ELEEL

Function

Catalytic activity

Cofactor

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Pathway

Carbohydrate biosynthesis; gluconeogenesis.

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionGTP binding
Molecular Functionkinase activity
Molecular Functionmanganese ion binding
Molecular Functionphosphoenolpyruvate carboxykinase (GTP) activity
Biological Processcellular response to dexamethasone stimulus
Biological Processcellular response to glucose stimulus
Biological Processcellular response to insulin stimulus
Biological Processdicarboxylic acid metabolic process
Biological Processgluconeogenesis
Biological Processglycerol biosynthetic process from pyruvate
Biological Processhepatocyte differentiation
Biological Processphosphorylation
Biological Processpropionate catabolic process
Biological Processresponse to starvation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
  • EC number
  • Alternative names
    • Serine-protein kinase PCK1

Gene names

    • Name
      pck1

Organism names

Accessions

  • Primary accession
    A0A4W4GHH1

Proteomes

Subcellular Location

PTM/Processing

Keywords

Interaction

Subunit

Monomer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain59-287Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Domain291-650Phosphoenolpyruvate carboxykinase C-terminal P-loop

Sequence similarities

Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    654
  • Mass (Da)
    72,990
  • Last updated
    2019-09-18 v1
  • MD5 Checksum
    56785863627E7F76E971E03933758342
MDKTSSDDASKKPLASYVCGSKFYSRSVEPCHVNLQSQDKSYPQVLQGDLGSLSPALREFIESSMSLCQPDSLHICDGSEEENKAILAQLQEQSMIKKLTKYENCWLARTDPCDVARVESRTVIVTQKKCETVPSPCGGGISQLGRWMSEKEWDKALNERFPGCMKGRTMYVIPFSMGPVGSPLSKIGVELTDSAYVVVSMRVMTRMGKSVLNTLGNGDFVRCLHTVGCPLPLKKPLVNNWPCNPELTLIAHIPDQRKIMSFGSGYGGNSLLGKKCFALRIASRMAKEEGWLAEHMLILGITNPAGNKRYIAAAFPSACGKTNLAMLSPTLPGWKVECVGDDIAWMKFDEEGHLRAINPENGFFGVAPGTSTKSNPNAMKTICRNTIFTNVAETSEGGVYWEGMDQKPPEGVTITSWKNKPWIPKDGEPSAHPNSRFCTPACQCPIIDPQWESPKGVPIEAIIFGGRRPEGVPLVYESFSWAHGVFVGATMRSEATAAAEHKNKVIMHDPFAMRPFFGYNFGHYLAHWLSIEQRPNTKLPKIFHVNWFRKSSSGRYLWPGYGENIRVLEWIFRRMNGEAGVMPSAVGYLPGNGSLNLSGLKESVNLDELFDISREFWEKEVQDIRMYFDQEVNNDLPTEIDRQLEMLTQRVRQL

Computationally mapped potential isoform sequences

There are 7 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A4W4GHH5A0A4W4GHH5_ELEELpck1635
A0A4W4GHJ5A0A4W4GHJ5_ELEELpck1645
A0A4W4GG12A0A4W4GG12_ELEELpck1624
A0A4W4GK52A0A4W4GK52_ELEELpck1631
A0A4W4GK75A0A4W4GK75_ELEELpck1619
A0A4W4GK24A0A4W4GK24_ELEELpck1626
A0A4W4GKR7A0A4W4GKR7_ELEELpck1610

Keywords

Genome annotation databases

Similar Proteins

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