A0A4W4GHH1 · A0A4W4GHH1_ELEEL
- ProteinPhosphoenolpyruvate carboxykinase, cytosolic [GTP]
- Genepck1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids654 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- L-seryl-[protein] + GTP = O-phospho-L-seryl-[protein] + GDP + H+This reaction proceeds in the forward direction.
Cofactor
Pathway
Carbohydrate biosynthesis; gluconeogenesis.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | GTP binding | |
Molecular Function | kinase activity | |
Molecular Function | manganese ion binding | |
Molecular Function | phosphoenolpyruvate carboxykinase (GTP) activity | |
Biological Process | cellular response to dexamethasone stimulus | |
Biological Process | cellular response to glucose stimulus | |
Biological Process | cellular response to insulin stimulus | |
Biological Process | dicarboxylic acid metabolic process | |
Biological Process | gluconeogenesis | |
Biological Process | glycerol biosynthetic process from pyruvate | |
Biological Process | hepatocyte differentiation | |
Biological Process | phosphorylation | |
Biological Process | propionate catabolic process | |
Biological Process | response to starvation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphoenolpyruvate carboxykinase, cytosolic [GTP]
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Gymnotiformes > Gymnotoidei > Gymnotidae > Electrophorus
Accessions
- Primary accessionA0A4W4GHH1
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Keywords
- PTM
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 59-287 | Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal | |||
Domain | 291-650 | Phosphoenolpyruvate carboxykinase C-terminal P-loop | |||
Sequence similarities
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length654
- Mass (Da)72,990
- Last updated2019-09-18 v1
- MD5 Checksum56785863627E7F76E971E03933758342
Computationally mapped potential isoform sequences
There are 7 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A4W4GHH5 | A0A4W4GHH5_ELEEL | pck1 | 635 | ||
A0A4W4GHJ5 | A0A4W4GHJ5_ELEEL | pck1 | 645 | ||
A0A4W4GG12 | A0A4W4GG12_ELEEL | pck1 | 624 | ||
A0A4W4GK52 | A0A4W4GK52_ELEEL | pck1 | 631 | ||
A0A4W4GK75 | A0A4W4GK75_ELEEL | pck1 | 619 | ||
A0A4W4GK24 | A0A4W4GK24_ELEEL | pck1 | 626 | ||
A0A4W4GKR7 | A0A4W4GKR7_ELEEL | pck1 | 610 |
Keywords
- Technical term