A0A4W4EFY7 · A0A4W4EFY7_ELEEL

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.
chloride (UniProtKB | Rhea| CHEBI:17996 )

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site375Proton acceptor 1
Active site375Proton acceptor 2
Active site505Proton donor 1
Active site505Proton donor 2

GO annotations

AspectTerm
Cellular Componentapical plasma membrane
Cellular Componentcilium
Cellular Componentcytoplasm
Cellular Componentextracellular space
Molecular Functioncarboxypeptidase activity
Molecular Functionmetal ion binding
Molecular Functionmetallopeptidase activity
Molecular Functionpeptidyl-dipeptidase activity
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Angiotensin-converting enzyme
  • EC number

Gene names

    • Name
      ace2

Organism names

Accessions

  • Primary accession
    A0A4W4EFY7

Proteomes

Subcellular Location

Apical cell membrane
Cell membrane
; Single-pass type I membrane protein
Cell projection, cilium
Cytoplasm
Secreted

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane750-771Helical

Keywords

PTM/Processing

Features

Showing features for signal, chain, glycosylation, disulfide bond.

Type
IDPosition(s)Description
Signal1-20
ChainPRO_502146130921-782Angiotensin-converting enzyme
Glycosylation55N-linked (GlcNAc...) asparagine
Disulfide bond132↔140
Disulfide bond343↔361
Disulfide bond530↔542

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain623-782Collectrin-like

Sequence similarities

Belongs to the peptidase M2 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    782
  • Mass (Da)
    90,066
  • Last updated
    2019-09-18 v1
  • MD5 Checksum
    71731BDCFA0545940E4E95D184013930
VCAMFVWCLLVLAVAPAASAQTTEDRAREFLKKFDEDATRLMYQYSLASWEYNTNITTANSDKLAEQGAIWSEFYSRASNESSAFPIDQMTDPEIQLQLRLLLDKGSGVLSADKLSRVLNEMSTIYGTGTVCKIDDPFDCQTLEPGLEAIMANSRDYYERLHVWEGWRVQVGKRMRPLYEDYVELKNEVARLNDYKDHGDYWRANYETIDEPKYSYNRDELMTDVRRIYHEIMPLYKELHAYVRAKLQKTYPGYIASDGGLPAHLLGDMWGRFWTNLYPLSVPFPEKPDIDVTSEMKAQGWKERRLFEEAETFFISVGMFAMFSNFWTNSMLVKPDDGSSVVCHATAWDMGNREDFRIKMCTKVNMDDFLTAHHEMGHNQYQMAYRHLPYLLRDGANEGFHEAVGEIMSLSAATPSHLQSLGLLPPDFTEDTETEINFLLKQALTIVATLPFTYMLEEWRWQVFQGSIPREQWMLRWWEMKRELVGVVEPLPRDETYCDPAALFHVSGDYSFIRYFTRTIYQFQFQDALCKEAGHTGPLYKCDITNATKAGIKLRQMLELGRSKSWTRALEQVSAHTRMDAQPLLNYFSTLYDWLRVENQKTNNHPGWNVAHDPCELLKNSYSENAIKVRLSLKAALGENAYPWNGNELYLFKASMAYAMRQYYLETKGEEANFMSENIHTYKETPRISFYFVVTHPTNASRILPKAEVEAAIWTSRGRINAVFQLNDATLEFEGLRATLAPPTEQPANMWLAVFGGVMGVTVCAGAYLVITGTRVESAFAF

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A4W4EE33A0A4W4EE33_ELEELace2780

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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