A0A4W4E6F7 · A0A4W4E6F7_ELEEL
- ProteinAcyl-coenzyme A oxidase
- Geneacox1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids664 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + O2 = (2E,5Z,8Z,11Z,14Z,17Z)-icosahexaenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + O2 = (2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- octadecanoyl-CoA + O2 = (2E)-octadecenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- octanoyl-CoA + O2 = (2E)-octenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- tetradecanoyl-CoA + O2 = (2E)-tetradecenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- decanoyl-CoA + O2 = (2E)-decenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- dodecanoyl-CoA + O2 = (2E)-dodecenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- glutaryl-CoA + O2 = (2E)-glutaconyl-CoA + H2O2This reaction proceeds in the forward direction.
- hexanoyl-CoA + O2 = (2E)-hexenoyl-CoA + H2O2This reaction proceeds in the forward direction.
Cofactor
Pathway
Lipid metabolism; peroxisomal fatty acid beta-oxidation.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 139 | FAD (UniProtKB | ChEBI) | |||
Binding site | 178 | FAD (UniProtKB | ChEBI) | |||
Active site | 421 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | peroxisome | |
Molecular Function | FAD binding | |
Molecular Function | fatty acid binding | |
Molecular Function | palmitoyl-CoA oxidase activity | |
Biological Process | fatty acid beta-oxidation using acyl-CoA oxidase | |
Biological Process | lipid homeostasis | |
Biological Process | very long-chain fatty acid metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameAcyl-coenzyme A oxidase
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Gymnotiformes > Gymnotoidei > Gymnotidae > Electrophorus
Accessions
- Primary accessionA0A4W4E6F7
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 15-133 | Acyl-coenzyme A oxidase N-terminal | |||
Domain | 136-245 | Acyl-CoA oxidase/dehydrogenase middle | |||
Domain | 275-436 | Acyl-CoA oxidase C-alpha1 | |||
Domain | 491-660 | Acyl-CoA oxidase C-terminal | |||
Sequence similarities
Belongs to the acyl-CoA oxidase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length664
- Mass (Da)74,244
- Last updated2019-09-18 v1
- MD5 ChecksumB5051154E958316D76CC1D0813521A02
Computationally mapped potential isoform sequences
There are 4 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A4W4E6Q7 | A0A4W4E6Q7_ELEEL | acox1 | 668 | ||
A0A4W4E7V8 | A0A4W4E7V8_ELEEL | acox1 | 663 | ||
A0A4W4E7T4 | A0A4W4E7T4_ELEEL | acox1 | 665 | ||
A0A4W4E8Y7 | A0A4W4E8Y7_ELEEL | acox1 | 668 |
Keywords
- Technical term