A0A4W4E605 · A0A4W4E605_ELEEL

Function

function

Glycosyltransferase that catalyze the transfer of GlcNAc from UDP-GlcNAc to the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans through a beta1-4 linkage and participates in the production of tri- and tetra-antennary N-linked sugar chains. Involved in glucose transport by mediating SLC2A2/GLUT2 glycosylation, thereby controlling cell-surface expression of SLC2A2 in pancreatic beta cells.

Catalytic activity

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Pathway

Protein modification; protein glycosylation.

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum
Cellular Componentendoplasmic reticulum-Golgi intermediate compartment
Cellular Componentextracellular region
Cellular ComponentGolgi stack
Cellular Componentmembrane
Molecular Functionacetylglucosaminyltransferase activity
Molecular Functionmetal ion binding
Biological Processprotein N-linked glycosylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
  • EC number
  • Alternative names
    • N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVa
    • UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVa

Gene names

    • Name
      MGAT4A

Organism names

Accessions

  • Primary accession
    A0A4W4E605

Proteomes

Subcellular Location

Keywords

PTM/Processing

Keywords

Family & Domains

Sequence similarities

Belongs to the glycosyltransferase 54 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    533
  • Mass (Da)
    61,420
  • Last updated
    2019-09-18 v1
  • MD5 Checksum
    6D3E2F65E94819751DBD9E75E63EA4B2
MRLRNGAVTTAVVFFTSFLSLSWYTAWQNGKEKLVAYQREFHALRERLRAAEQRTLQRSSELNSILEQFRHAIAETNGSKDALNNFSDETQKLLKQLVHRKPLQVPNIYHHLPHLLNNDGSLRPAVQVGQGRTGVSMVMGIPTVKRKVKSYLSETLRSLIDKLSAEEKLDCVIVVFIGETDIDYVHSVVSGLEKEFFKELNSGLLEVISPPASYYPDLNNLKETFGDSRERVKWRTKQNLDYSFLMMYSVSKGVYYVQLEDDIVAKSNYFATMKNFAMQLASEDWMILEFSQLGFIGKMFQAPDLNLIVEFIFMFYKEKPIDWLLDHVLWVKVCNPEKDAKHCERQKSSLRIRFRPSLFQHVGLHSSLAGKIQKLTDKDFLKPLLHKIHVNPPAEVSTSLKVYQGHTLEKTYTGEDFFWAITPMAGDYVLFKFDRPVSIERFLFRSGNQEHPGDQIKNTTVEILPFLDTELKTKEKYKRTEDRFYRIAEFEKGVAEGSLDPAFNPVAAVRLTVQKDSAVWAIISEIHIKRVAG

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A4W4E5N4A0A4W4E5N4_ELEELMGAT4A547

Keywords

Genome annotation databases

Similar Proteins

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