A0A4W4DR67 · A0A4W4DR67_ELEEL
- ProteinCytosolic purine 5'-nucleotidase
- Genent5c2a
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids519 (go to sequence)
- Protein existenceInferred from homology
- Annotation score5/5
Function
Catalytic activity
- AMP + inosine = adenosine + IMP
- CMP + inosine = cytidine + IMP
- GMP + H2O = guanosine + phosphateThis reaction proceeds in the forward direction.
- GMP + inosine = guanosine + IMP
- H2O + XMP = phosphate + xanthosineThis reaction proceeds in the forward direction.
- dGMP + H2O = 2'-deoxyguanosine + phosphateThis reaction proceeds in the forward direction.
- dGMP + inosine = 2'-deoxyguanosine + IMP
- dIMP + H2O = 2'-deoxyinosine + phosphateThis reaction proceeds in the forward direction.
- dIMP + inosine = 2'-deoxyinosine + IMP
- inosine + UMP = IMP + uridine
Cofactor
Note: Binds 1 Mg2+ ion per subunit.
Features
Showing features for active site, binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | 5'-nucleotidase activity | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | transferase activity | |
Biological Process | GMP metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCytosolic purine 5'-nucleotidase
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Gymnotiformes > Gymnotoidei > Gymnotidae > Electrophorus
Accessions
- Primary accessionA0A4W4DR67
Proteomes
Subcellular Location
Interaction
Subunit
Homotetramer.
Structure
Family & Domains
Features
Showing features for region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 490-519 | Disordered | ||||
Sequence: EIQPPHLFPQTPQEITHCHDEDDDEEEEEE |
Sequence similarities
Belongs to the 5'(3')-deoxyribonucleotidase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length519
- Mass (Da)59,831
- Last updated2019-09-18 v1
- ChecksumCC206D87F19F467F
Computationally mapped potential isoform sequences
There are 4 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A4W4DR78 | A0A4W4DR78_ELEEL | nt5c2a | 568 | ||
A0A4W4DRF4 | A0A4W4DRF4_ELEEL | nt5c2a | 524 | ||
A0A4W4DRI3 | A0A4W4DRI3_ELEEL | nt5c2a | 378 | ||
A0A4W4DS80 | A0A4W4DS80_ELEEL | nt5c2a | 564 |
Keywords
- Technical term