A0A4W4DPY7 · A0A4W4DPY7_ELEEL

Function

function

Cadherins are calcium-dependent cell adhesion proteins.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentadherens junction
Cellular Componentcatenin complex
Molecular Functioncadherin binding
Molecular Functioncalcium ion binding
Biological Processadherens junction organization
Biological Processcalcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
Biological Processcell morphogenesis
Biological Processcell-cell adhesion mediated by cadherin
Biological Processcell-cell junction assembly
Biological Processepithelium development
Biological Processhomophilic cell adhesion via plasma membrane adhesion molecules

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Cadherin 12, type 2a (N-cadherin 2)

Gene names

    • Name
      cdh12a

Organism names

Accessions

  • Primary accession
    A0A4W4DPY7

Proteomes

Subcellular Location

Cell membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane590-611Helical

Keywords

PTM/Processing

Keywords

Family & Domains

Features

Showing features for domain, compositional bias, region.

Type
IDPosition(s)Description
Domain59-139Cadherin
Domain140-248Cadherin
Domain260-358Cadherin
Domain359-463Cadherin
Domain463-581Cadherin
Compositional bias633-650Basic and acidic residues
Region633-684Disordered

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    759
  • Mass (Da)
    83,241
  • Last updated
    2019-09-18 v1
  • MD5 Checksum
    6CA6AF7EEBD142E95B5C56248318ED11
LPEALCLRLGKEHHRGLWDHRRHGVAGLQRVKRGWVWNQFFVLEEYMGSEPQYVGKLHSDLDKGDNLVKYTLSGEGVGSIFTVEPTTGDIHAVQSLDREVKPYYTLRAQAVDVLTGRPLEPESQFIIKVQDINDNEPRFLEGPYSASVPEMSPIGTYVMQVTATDADDPTYGNSARVVYSILHGQPYFSVDPKTGVIRIALPNMDREVKESYQVLIQAKDMGGQLGGLAGTTTINITLTDVNDNPPRFKMCRQISTHVASSIGRVKAHDLDLGKNAEVEYSIIPGDGSSTFDIYTDEHTQEGVVLLKKPLDYESRKVYSFKVEASNAQPNAAFLHPGAFKDSATLRVSVLDVEEPPAFSQGSYGMEAYEDSPVGSIIGAVTAEDLDAGDSPIRYSIEWRNSSENYFDVDPTEGTISTREALDREKTARHNVTVVATKVNNPLLFSRVSVAVDVLDVNEFPPELSFPYEMFVCEDAKVGQVIRVLGATDRDMPHTGHRFFFKSPKDIRNRNFTIRDYGNNTAGVVTRRAGLQRSETSVHLIPVVVEDSGYPVLSSTATLSVQVCPCTRDSRSTAACGTRAAFLPAGLSTGALVAVPLCLLVLLATAALHVALKRHKKTGTLMSSEEDVRDNVIHYDDEGGGEEDTRAFDIGTLRHTKAATDTPPRGEAGSRPRPPSLAGPPPADSVDLRAYIQQRLQESHSATAAPPYDSLATYAYEGEGSAAGSLSSIESHMQEPEQDYSRMADWGPHFKTLARIFTDE

Computationally mapped potential isoform sequences

There are 9 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A4W4DQ89A0A4W4DQ89_ELEELcdh12a814
A0A4W4DPV5A0A4W4DPV5_ELEELcdh12a538
A0A4W4DPY8A0A4W4DPY8_ELEELcdh12a595
A0A4W4DQ82A0A4W4DQ82_ELEELcdh12a806
A0A4W4DQ28A0A4W4DQ28_ELEELcdh12a441
A0A4W4DPN5A0A4W4DPN5_ELEELcdh12a768
A0A4W4DQB6A0A4W4DQB6_ELEELcdh12a811
A0A4W4DR94A0A4W4DR94_ELEELcdh12a796
A0A4W4DQU4A0A4W4DQU4_ELEELcdh12a778

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias633-650Basic and acidic residues

Keywords

Genome annotation databases

Similar Proteins

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