A0A4W3K6H1 · A0A4W3K6H1_CALMI
- ProteinAldehyde dehydrogenase
- GeneALDH3A2
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids409 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- (2E)-hexadecenal + NAD+ + H2O = (E)-hexadec-2-enoate + NADH + 2 H+
- hexadecanoate + NADH + 2 H+ = hexadecanal + NAD+ + H2O
- 2,6,10,14-tetramethylpentadecanal + NAD+ + H2O = 2,6,10,14-tetramethylpentadecanoate + NADH + 2 H+
- 22-oxodocosanoate + NAD+ + H2O = docosanedioate + NADH + 2 H+
- octadecanal + NAD+ + H2O = octadecanoate + NADH + 2 H+
- octanal + NAD+ + H2O = octanoate + NADH + 2 H+
- tetradecanal + NAD+ + H2O = tetradecanoate + NADH + 2 H+
- heptanal + NAD+ + H2O = heptanoate + NADH + 2 H+
- a fatty aldehyde + NAD+ + H2O = a fatty acid + NADH + 2 H+
- decanal + NAD+ + H2O = decanoate + NADH + 2 H+
- dodecanoate + NADH + 2 H+ = dodecanal + NAD+ + H2O
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 208 | |||||
Sequence: E | ||||||
Active site | 242 | |||||
Sequence: C |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum membrane | |
Molecular Function | 3-chloroallyl aldehyde dehydrogenase activity | |
Molecular Function | aldehyde dehydrogenase (NAD+) activity | |
Biological Process | cellular aldehyde metabolic process | |
Biological Process | fatty acid metabolic process |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameAldehyde dehydrogenase
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Chondrichthyes > Holocephali > Chimaeriformes > Callorhinchidae > Callorhinchus
Accessions
- Primary accessionA0A4W3K6H1
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Endoplasmic reticulum membrane ; Single-pass membrane protein
Keywords
- Cellular component
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 4-404 | Aldehyde dehydrogenase | ||||
Sequence: EAVAGARMAYRTGRTRPLAFRVKQLKALQKMLTENEDKIFQALKKDLHKSQFDVAIFEVVGLQNEITLALNKLPDWTAPEFVSKNMLTIMDEVYIHREPLGVVLIMGAWNYPLALVIQPLIGAIAAGNAVVIKPSEVSENMAQLLQKLLPQYLDKELYPVVNGAVPETTELLKLQFDHILFTGSSSVGKIVMEAAAKHLTPVTLELGGKSPCYINKNCNLDVACRRIAWARYVNCGQTCIAPDYILCDEGIHDKVVQKLIESIKMFYGDDPQTSPDYGRIVNRHHLSRLLSLLEGLKVTHGGDYNTQQLYLAPTIVANVDPNAKVMQEEIFGPVLPIVPVAGAEDAINFINNRDKPLALYIFTNDKKLINRMIAETSSGGVTVNDCMIHYSISSLPFGGIG |
Sequence similarities
Belongs to the aldehyde dehydrogenase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length409
- Mass (Da)45,256
- Last updated2019-09-18 v1
- Checksum4AD3F12A6E5E9655
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A4W3JVW3 | A0A4W3JVW3_CALMI | ALDH3A2 | 492 | ||
V9KQM4 | V9KQM4_CALMI | ALDH3A2 | 488 |
Keywords
- Technical term