A0A4W3K3S2 · A0A4W3K3S2_CALMI
- ProteinSodium-coupled neutral amino acid symporter 2
- Geneslc38a2
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids451 (go to sequence)
- Protein existencePredicted
- Annotation score4/5
Function
Catalytic activity
- L-alanine(in) + Na+(in) = L-alanine(out) + Na+(out)This reaction proceeds in the backward direction.L-alanine (in)CHEBI:57972
+ Na+ (in)CHEBI:29101= L-alanine (out)CHEBI:57972+ Na+ (out)CHEBI:29101 - L-asparagine(in) + Na+(in) = L-asparagine(out) + Na+(out)This reaction proceeds in the backward direction.
- L-glutamine(in) + Na+(in) = L-glutamine(out) + Na+(out)This reaction proceeds in the backward direction.
- L-histidine(in) + Na+(in) = L-histidine(out) + Na+(out)This reaction proceeds in the backward direction.
- L-leucine(in) + Na+(in) = L-leucine(out) + Na+(out)This reaction proceeds in the backward direction.
- L-methionine(in) + Na+(in) = L-methionine(out) + Na+(out)This reaction proceeds in the backward direction.
- L-phenylalanine(in) + Na+(in) = L-phenylalanine(out) + Na+(out)This reaction proceeds in the backward direction.
- L-proline(in) + Na+(in) = L-proline(out) + Na+(out)This reaction proceeds in the backward direction.
- L-serine(in) + Na+(in) = L-serine(out) + Na+(out)This reaction proceeds in the backward direction.
- L-threonine(in) + Na+(in) = L-threonine(out) + Na+(out)This reaction proceeds in the backward direction.
- glycine(in) + Na+(in) = glycine(out) + Na+(out)This reaction proceeds in the backward direction.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | L-glutamine transmembrane transporter activity |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameSodium-coupled neutral amino acid symporter 2
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Chondrichthyes > Holocephali > Chimaeriformes > Callorhinchidae > Callorhinchus
Accessions
- Primary accessionA0A4W3K3S2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 69-90 | Helical | ||||
Sequence: FGISAFNLSNAIMGSGILGLAY | ||||||
Transmembrane | 97-119 | Helical | ||||
Sequence: IVLFVILLSAVSIFSLYSVHLLL | ||||||
Transmembrane | 161-180 | Helical | ||||
Sequence: YLYIVKYELPLVILAFLNLT | ||||||
Transmembrane | 192-215 | Helical | ||||
Sequence: WLVIIVSIVLILPLSLLKNLGNYL | ||||||
Transmembrane | 235-254 | Helical | ||||
Sequence: ITVYAVPILTFAFVCHPAVL | ||||||
Transmembrane | 274-295 | Helical | ||||
Sequence: VSFLGIFVMYLLAAVFGYLTFY | ||||||
Transmembrane | 315-338 | Helical | ||||
Sequence: VLLVVRLAVLMAVTLTVPVVLFPI | ||||||
Transmembrane | 359-378 | Helical | ||||
Sequence: LITVIILGLANCLVIFVPTI | ||||||
Transmembrane | 384-405 | Helical | ||||
Sequence: FMGASAAAMLIFILPSAFYIKL | ||||||
Transmembrane | 417-439 | Helical | ||||
Sequence: IGALIFLICGIFVMISSMTLIIL |
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-25 | Disordered | ||||
Sequence: MNRFNISPDDDSSSTNSNEYNYTEN | ||||||
Domain | 66-213 | Amino acid transporter transmembrane | ||||
Sequence: NTSFGISAFNLSNAIMGSGILGLAYAMANTGIVLFVILLSAVSIFSLYSVHLLLKTSKEGGSLLYEQLGQRAFGMPGKVAASVSITMQNFGAMSSYLYIVKYELPLVILAFLNLTENTGHWYLNGDWLVIIVSIVLILPLSLLKNLGN | ||||||
Domain | 236-438 | Amino acid transporter transmembrane | ||||
Sequence: TVYAVPILTFAFVCHPAVLPIYEELKDRSRKKMQRVANVSFLGIFVMYLLAAVFGYLTFYGHVEPELLHTYSKVYKFDTVLLVVRLAVLMAVTLTVPVVLFPIRTSVQQLLFPSKEFNWVRHSLITVIILGLANCLVIFVPTIRDIFGFMGASAAAMLIFILPSAFYIKLVKKESMKSVQKIGALIFLICGIFVMISSMTLII |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length451
- Mass (Da)50,201
- Last updated2019-09-18 v1
- Checksum816CFDD7A0D6F038
Computationally mapped potential isoform sequences
There are 9 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A4W3J8V5 | A0A4W3J8V5_CALMI | slc38a2 | 518 | ||
A0A4W3J673 | A0A4W3J673_CALMI | slc38a2 | 425 | ||
A0A4W3J909 | A0A4W3J909_CALMI | slc38a2 | 487 | ||
A0A4W3J8X2 | A0A4W3J8X2_CALMI | slc38a2 | 502 | ||
A0A4W3JKP5 | A0A4W3JKP5_CALMI | slc38a2 | 475 | ||
A0A4W3JKQ0 | A0A4W3JKQ0_CALMI | slc38a2 | 437 | ||
A0A4W3JKR1 | A0A4W3JKR1_CALMI | slc38a2 | 443 | ||
A0A4W3K3R3 | A0A4W3K3R3_CALMI | slc38a2 | 493 | ||
A0A4W3K3T0 | A0A4W3K3T0_CALMI | slc38a2 | 431 |
Keywords
- Technical term