A0A4W3GI29 · A0A4W3GI29_CALMI
- ProteinAcyl-coenzyme A oxidase
- Geneacox1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids577 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + O2 = (2E,5Z,8Z,11Z,14Z,17Z)-icosahexaenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + O2 = (2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- octadecanoyl-CoA + O2 = (2E)-octadecenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- octanoyl-CoA + O2 = (2E)-octenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- tetradecanoyl-CoA + O2 = (2E)-tetradecenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- decanoyl-CoA + O2 = (2E)-decenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- dodecanoyl-CoA + O2 = (2E)-dodecenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- glutaryl-CoA + O2 = (2E)-glutaconyl-CoA + H2O2This reaction proceeds in the forward direction.
- hexanoyl-CoA + O2 = (2E)-hexenoyl-CoA + H2O2This reaction proceeds in the forward direction.
Cofactor
Pathway
Lipid metabolism; peroxisomal fatty acid beta-oxidation.
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | peroxisome | |
Molecular Function | FAD binding | |
Molecular Function | fatty acid binding | |
Molecular Function | palmitoyl-CoA oxidase activity | |
Biological Process | fatty acid beta-oxidation using acyl-CoA oxidase | |
Biological Process | lipid homeostasis | |
Biological Process | very long-chain fatty acid metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameAcyl-coenzyme A oxidase
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Chondrichthyes > Holocephali > Chimaeriformes > Callorhinchidae > Callorhinchus
Accessions
- Primary accessionA0A4W3GI29
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 13-49 | Acyl-coenzyme A oxidase N-terminal | ||||
Sequence: LSPLDLHLGMFLPTILNQATPEQQDRFFMPAWNLQII | ||||||
Domain | 52-161 | Acyl-CoA oxidase/dehydrogenase middle | ||||
Sequence: YAQTEMGHGTFLRGLETTATYDPSTQEFVLNSPTVTSIKWWPGGLGKTSNHAIVLAQLYTQGQCRGLHAFIVPIRKMGTHEPLPGVVVGDIGPKFGYDEVDNGYLKLENV | ||||||
Domain | 191-351 | Acyl-CoA oxidase C-alpha1 | ||||
Sequence: YGTMVFIRSMIVSDSARALSQACTIAIRYSAVRHQSELKPGAPEPQIIDYQTQQYKLFPFLATAYAFRFVGNFMADMYHRITGDINEGDYSELPELHSLSAGLKAFTSWVASAGIEECRMACGGHGYSRSSGLPDIYVTFTPSCTYEGENTVMMLQTARYL | ||||||
Domain | 396-573 | Acyl-CoA oxidase C-terminal | ||||
Sequence: LGSLVEAYKMRAATLVDGAAQNYQSELARRKSKDEAWNNTSIDLVRASQAHCHYVVVKLFTAKLSEISDTAIHEALSSLCLMYALHGISKNSGDFLQAGILNDPQISQVHQRVKELLAVIRRNAVALVDAFDYPDAVLASVLGRYDGNVYENMFEWAKKSPLNKTEVHESFHKYLKPL |
Sequence similarities
Belongs to the acyl-CoA oxidase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length577
- Mass (Da)64,204
- Last updated2019-09-18 v1
- Checksum8D539FDBDA840D73
Computationally mapped potential isoform sequences
There are 9 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A4W3GHK6 | A0A4W3GHK6_CALMI | acox1 | 701 | ||
A0A4W3GH58 | A0A4W3GH58_CALMI | acox1 | 669 | ||
A0A4W3GHF7 | A0A4W3GHF7_CALMI | acox1 | 669 | ||
A0A4W3GHH9 | A0A4W3GHH9_CALMI | acox1 | 599 | ||
A0A4W3GHL5 | A0A4W3GHL5_CALMI | acox1 | 573 | ||
A0A4W3GHS1 | A0A4W3GHS1_CALMI | acox1 | 552 | ||
A0A4W3GY93 | A0A4W3GY93_CALMI | acox1 | 680 | ||
A0A4W3GYM3 | A0A4W3GYM3_CALMI | acox1 | 579 | ||
A0A4W3GYE8 | A0A4W3GYE8_CALMI | acox1 | 595 |
Keywords
- Technical term