A0A4W2GCA8 · A0A4W2GCA8_BOBOX

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasmic vesicle membrane
Cellular Componentlysosomal membrane
Cellular Componentplasma membrane
Molecular Functioncalcium ion binding
Molecular Functionintracellularly gated calcium channel activity
Molecular Functionmanganese ion transmembrane transporter activity
Molecular Functionmono-ADP-D-ribose binding
Biological Processcalcium ion import across plasma membrane
Biological Processcellular response to calcium ion
Biological Processcellular response to hydrogen peroxide
Biological Processcellular response to purine-containing compound
Biological Processcellular response to temperature stimulus
Biological Processdendritic cell chemotaxis
Biological Processdendritic cell differentiation
Biological Processprotein homotetramerization
Biological Processregulation of actin cytoskeleton organization
Biological Processregulation of filopodium assembly
Biological Processrelease of sequestered calcium ion into cytosol
Biological Processresponse to heat
Biological Processresponse to hydroperoxide
Biological Processtemperature homeostasis
Biological Processzinc ion transmembrane transport

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Transient receptor potential cation channel subfamily M member 2

Gene names

    • Name
      TRPM2

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos

Accessions

  • Primary accession
    A0A4W2GCA8

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane750-770Helical
Transmembrane790-813Helical
Transmembrane863-881Helical
Transmembrane930-947Helical
Transmembrane1019-1044Helical

Keywords

Family & Domains

Features

Showing features for compositional bias, region, domain.

TypeIDPosition(s)Description
Compositional bias1-15Basic and acidic residues
Region1-21Disordered
Region1200-1231Disordered
Compositional bias1217-1231Basic and acidic residues
Domain1350-1494Nudix hydrolase

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,499
  • Mass (Da)
    170,701
  • Last updated
    2019-09-18 v1
  • Checksum
    03B9D8D7B4B082C4
MELLAKRHRDQASSGEEDSFGVQPRRVADLAMVPNLRWSSTGLCRRTRSQCLFSSCEKQGDLSSWISDNIKKKECIYFVESSKLSDAGKVVCECGYPREQHLEEATGSHTFQGQEWDPKKHVREMPTDAFGDIVFTGLGQKVGKYVRLSQDTPSSLIYQLMTQQWGLDAPNLLISVTGGAKDFKMKPRLKSIFRRGLLKVAQTSGAWVITGGSHTGVMKQVGEAVRNFSLSGSFCEGEVVTIGIATWGALHNRESLIHPTGGFPAEYIVDEGGQGHLTCLDSNHSHFILVDDGTHGRYGVEIPLRTKLEKFISQQTKERGGVAIKIPIVCVVLEGGPGTLNTIYNAITNGTPCVVVEGSGRVADVIAQVAGLPISEITISLIQQKLSMFFQGMFETFTESKIVEWTKKIQDIVRRRQLLTVFREGKDGQQDVDVAILQALLKASRSLDHFGHENWDHQLNLAVAWNRVDIAQSEIFTDERQWKPSELYPMMVAALITNKPEFVKLFLENGVQLKEFVSQATLFYLYQNLEPTCLFHCKLDRVLGGEPERLDPGVLLQRVAQVLRELLGDSTQLLYSRPHSSDQQRLFTVPSVKISVQGVNPQSSYKHSSSQATFTIDPVRDLLIWAIVQNRRELAEIIWAQSQDCIAAALACSKILKELSKEEEDTDSLEEMLVLADEYEQRAIGVFTECYRQNEERAQKLLVRVSEAWGRTTCLQLALEAKDMKFVSHGGIQAYLTKVWWGQLSVDNGLWRLVLCMLVFPLLYTGLVSFRNRELQADRCLARVRAFFSAPVVVFHMNILSYFAFLCLFAYVLMVDFQPQPSSCECLIYVWLFSLVCEELRQLFYDPDGSGLRKAVLVYFSDYWNKLDVCAILLFIAGLTCRLMPSLLYTGRIILSLDFTMFCLRLMHIFTVSKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNERRVEWIFRGAIYHSYLTIFGQLPTYIDGVNFKPDQCSPNGTDPYKPKCPEIDQARQEPVFPEWLTVLLLCLYLLFANILLLNLLIAMFNYTFQQVQEHTDQIWKFQRHDLIEEYQGRPPAPPPFILLSHLHLIIKRVVLKIPAKRHKLFKNKLEKTEEAALLSWEMYLKENYLQEQQFQQKQRPEQKIQDVSDKVDSMVRLLEMAHLKQSGAMEQRLASLEEQVAQTATALHWIVKALRDSGFGSEEGVPTLAPQKASVGRDPELDSRSKAEDPDDAYHVNARHLLYPSCSVLRFPVPNEKVPWETEFLMYNPPFYTANRKDKDLVDPVGDALEPLSRISYNAVDGPLDRRSFHGVYTVRDGLPLNPMGRTGLRGRGDLSRFGPNHTLQPVITRWRRSLDGAICRKNVKKMLEVLVVKHGPSEHWMLPGGSREPGELLPQNLKQVLQREFWSSFERLLTQGMKVYKGYMDDPRNTDNAWIETVAVSIHFPDQSDVELKRLNSHLHSCDEGMAIRWQVVDERIPLYDNHKVILQKVAALFMAYY

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-15Basic and acidic residues
Compositional bias1217-1231Basic and acidic residues

Genome annotation databases

Similar Proteins

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