A0A4W2CCJ3 · A0A4W2CCJ3_BOBOX
- ProteinAnion exchange protein
- GeneSLC4A1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids930 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- chloride(out) + hydrogencarbonate(in) = chloride(in) + hydrogencarbonate(out)chloride (out)CHEBI:17996
+ hydrogencarbonate (in)CHEBI:17544= chloride (in)CHEBI:17996+ hydrogencarbonate (out)CHEBI:17544
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | monoatomic anion transmembrane transporter activity | |
Molecular Function | solute:inorganic anion antiporter activity |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameAnion exchange protein
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos
Accessions
- Primary accessionA0A4W2CCJ3
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 423-446 | Helical | ||||
Sequence: VLSAIIFIYFAALTPAITFGGLLG | ||||||
Transmembrane | 458-489 | Helical | ||||
Sequence: LLLSTALQGIIFSLLGAQPLLVLGFSGPLLVF | ||||||
Transmembrane | 509-534 | Helical | ||||
Sequence: VWIGFWLILLVVLVVAFEGSFLVRFI | ||||||
Transmembrane | 541-563 | Helical | ||||
Sequence: IFSFLISLIFIYETFYKLVTIFQ | ||||||
Transmembrane | 583-602 | Helical | ||||
Sequence: AALPNTALLSLVLMAGTFFL | ||||||
Transmembrane | 622-642 | Helical | ||||
Sequence: IIGDFGVPISILIMVMVDALI | ||||||
Transmembrane | 677-698 | Helical | ||||
Sequence: FPIWMMFASALPALLVFILIFL | ||||||
Transmembrane | 719-742 | Helical | ||||
Sequence: GFHLDLLLIIGMGGVGAIFGMPWL | ||||||
Transmembrane | 779-798 | Helical | ||||
Sequence: ISGLLVAVLVGVSILMGPVL | ||||||
Transmembrane | 805-829 | Helical | ||||
Sequence: VLFGIFLYMGVTSLSGIQLFDRVLL | ||||||
Transmembrane | 849-868 | Helical | ||||
Sequence: WRMHLFTITQIVCLVVLWVV | ||||||
Transmembrane | 875-897 | Helical | ||||
Sequence: SLALPFILILTVPLRRFLLPFIF |
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-15 | Acidic residues | ||||
Sequence: MGDPEEYEDQLEETL | ||||||
Region | 1-39 | Disordered | ||||
Sequence: MGDPEEYEDQLEETLEQKEYEDHDSVSIPMEEAEGDTIQ | ||||||
Compositional bias | 16-30 | Basic and acidic residues | ||||
Sequence: EQKEYEDHDSVSIPM | ||||||
Domain | 65-341 | Band 3 cytoplasmic | ||||
Sequence: HKVCVQLRELVMDEKNQEIQWMETARWVGLEENLGKDGIWGRPHLPYLNFWSLLELQKAFAKGTVLLDLPGKSLAEVANQLLDRFTFEGQIQPDDQDNLLRVLLLKHSHASDMEALGGVKPVVVTHSGDPSEPLLPQHPSLETELFCEQGEGSTRGHAPEILGKSPQDWEATLVLVGCARFLKRPVLGFVRLKEPMEPEPKPEGSEEPAVPVRFLIVLLGPEGPNINYTQLGRAAATLMSERVFWNDAYLAQSKETLVQSLEGFLDCSLVLPPLDAP | ||||||
Domain | 395-570 | Bicarbonate transporter-like transmembrane | ||||
Sequence: KLFGGLVRDIRRRYPRYLSDITDALSPQVLSAIIFIYFAALTPAITFGGLLGDKTENMIGVSELLLSTALQGIIFSLLGAQPLLVLGFSGPLLVFEEAFYSFCQTNNLEYIVGRVWIGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFYKLVTIFQDHPLQKN | ||||||
Domain | 581-908 | Bicarbonate transporter-like transmembrane | ||||
Sequence: PQAALPNTALLSLVLMAGTFFLAMMLRKFKNSSYFPGKLRRIIGDFGVPISILIMVMVDALIQDTYTQKLSVPEGLSVSNPTERDWLIHPLGIRVEFPIWMMFASALPALLVFILIFLESQITTLIISKPERKMVKGSGFHLDLLLIIGMGGVGAIFGMPWLSATTVRTVTHANALTVMSKDSTPGAVSQIQGVKEQRISGLLVAVLVGVSILMGPVLRHIPLAVLFGIFLYMGVTSLSGIQLFDRVLLLLKPRKYYPEVPYARRVKTWRMHLFTITQIVCLVVLWVVRSIKQISLALPFILILTVPLRRFLLPFIFRDMELKLLDAD |
Sequence similarities
Belongs to the anion exchanger (TC 2.A.31) family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length930
- Mass (Da)104,375
- Last updated2019-09-18 v1
- Checksum4F6AADFEBAF6A3A1
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A4W2CCN0 | A0A4W2CCN0_BOBOX | SLC4A1 | 1059 | ||
A0A4W2E908 | A0A4W2E908_BOBOX | SLC4A1 | 1029 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-15 | Acidic residues | ||||
Sequence: MGDPEEYEDQLEETL | ||||||
Compositional bias | 16-30 | Basic and acidic residues | ||||
Sequence: EQKEYEDHDSVSIPM |
Keywords
- Technical term